Introduction to Dermatology Flashcards

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1
Q

What is the largest organ in the body?

A

Skin

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2
Q

What are some skin adnexal structures?

A

Hair

Nails

Glands

Sensory structures

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3
Q

What are important functions of the skin?

A
  • Protection
  • Homeostasis
  • Transmission of sensation
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4
Q

What are the layers of the skin from superficial to deep?

A

Epidermis

Dermis

(then below but not part of the skin is the hypodermis)

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5
Q

What are the 5 layers of the epidermis ?

A

1- Stratum corneum-

2- Stratum lucidum

3- Stratum granulosum

4- Stratum spinosum

5- Stratum basale

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6
Q

What are the 3 different stages of the hair cycle?

A

1- Anagen

2- Catagen

3- Telogen

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7
Q

What is the anagen phase of hair cycle?

A

Active growing phase

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8
Q

What is the catagen phase of hair cycle?

A

lasts for 2-3 week,

is the dying phase where hair growth stops

and

follicles shrink

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9
Q

What is the telogen phase of hair cycle?

A

Is resting phase and lasts for 1-4 months

this is the shedding phase

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10
Q

How long does the telogen phase of hair cycle last?

A

1-4 months

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11
Q

How long does the catagen phase of hair growth last?

A

2-3 weeks

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12
Q

During what phase of the hair cycle is most hair grow?

A

Anagen (80-90% hair) the fastest phase

Telogen (up to 10% of hair)

Categen (1-3% of hair) the slowest phase

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13
Q

What are the six functions of the skin?

“important to know this, is a common exam question”

A
  • Thermoregulation
    • Insulation, heat transfer
  • Skin immune system
    • Innate and adaptive functions
  • Barrier
    • Protects against mechanical, chemical, microorganisms, UV light
    • Keep in water and electrolytes, macromolecules
  • Sensation
    • Temperature, touch and pain
  • Vitamin D synthesis
    • UV light converts 7-dehydrocholesterol to cholecalciferol
  • Interpersonal communication
    • Physical appearance, smell, self-identity
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14
Q

How much of skin disease is skin cancer/lesions?

A

50%

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15
Q

Why is skin disease important?

A
  • Disfigurement
  • Discomfort
  • Disability
  • Depression
  • Death
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16
Q

What are some causes of skin disease?

A
  • External
    • Temperature
      • Cold injury
        • Frostbite, chilblains
        • Skin necrosis
        • Cold urticaria
    • UV
      • Called photosensitivity
      • Commonly caused by medications
      • Exposed sites affected
      • Can be sensitive to UVA, UVB, visible light or a combination
    • Chemical
    • Infection (allergen or irritant)
    • Trauma
      • Dermatitis artefacta (skin lesions solely produced by patients own actions)
  • Internal
    • Systemic disease
    • Genetics
    • Drugs
      • Think of OTC drugs
    • Infection
    • Autoimmune
      • Bullous pemphigoid
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17
Q

What are chilblains?

A

Small lesions caused by inflammation of small blood vessels due to exposure to cold air

18
Q

What is cold urticaria?

A

is a skin reaction to cold that appears within minutes after cold exposure

19
Q

What is a skin lesion solely produced by patients own actions called?

A

Dermatitis artefacta

20
Q

What is an example of an autoimmune skin disease?

A

Bullous pemphigoid

21
Q

What is the morphology of a skin lesion?

A

Appearance of a skin lesion

22
Q

How big is a “small” skin lesion?

A

Typically means less than 5mm

23
Q

What are some descriptive words for skin lesions?

A
  • Macule
    • Small circumscribed area
  • Patch
    • Larger circumscribed area
  • Papule
    • Small raised area
  • Plaque
    • Larger raised area
  • Vesicle
    • Small fluid filled
  • Bulla
    • Large fluid filled
  • Pustule
    • Small pus filled
  • Abscess
    • Large pus filled
  • Erosion
    • Loss of epidermis
  • Ulcer
    • Loss of epidermis and dermis
24
Q

What is a macule?

A

1- Small flat circumscribed area

2- Non-palpable, change in skin color, with distinct borders

25
Q

What is a patch?

A

Larger flat circumscribed area

Non-palpable, change in skin color, with distinct borders

26
Q

What is a papule? “ paa-pi-yuul”

A

Small raised area

it is Palpable solid lesion, with less than 1 cm in diameter

27
Q

What is a plaque? “ ba-laa-Q”

A

Larger raised area

it is Palpable solid lesion, with greater than 1cm in diameter

28
Q

What is a vesicle?

A

Small fluid filled lesion, superficial with thin walls and less than 1cm diameter.

29
Q

What is a bulla? “ bu-la”

A

Large fluid filled lesion, superficial, with thin walls and greater than 1 cm in diameter.

30
Q

What is a pustule? “ Pas-je-yuul”

A

Small pus filled lesion, superficial with thin walls.

Picture shows acne in the background and Pustule

31
Q

What is an abscess?

A

Large pus filled lesion, with thick wall

32
Q

What is an erosion?

A

Loss of epidermis only

33
Q

What is an ulcer?

A

Loss of epidermis and dermis

34
Q

What are some examples of common skin conditions?

A
35
Q

What are some examples of skin conditions that can have cutaneous signs?

A
  • Erythema nodosum
  • Sarcoidosis
  • Vasculitis
  • Malignancy
  • Auto-immune conditions
36
Q

What is a skin sign of hyperlipidaemia?

A

Eruptive xanthoma

37
Q

What is Acanthosis Nigricans?

A

Brown to black, poorly defined, velvety hyperpigmentation of the skin

Hyperkeratosis and hyperpigmentation

38
Q

What is acanthosis nigricans associated with?

A

Associated with insulin resistance, obesity and malignancy.

39
Q

What investigations should be done if bacterial infection is suspected for a skin condition?

A
  • Charcoal swab
  • Ask for MC&S
    • Microscopy
    • Culture
    • Sensitivities
40
Q

What investigations should be done if viral infection is suspected for a skin condition?

A
  • Viral swab for PCR
  • Can swab vesicle/bulla if vesicular eruption
  • If systemic illness, can take throat swab
41
Q

What investigations should be done if Fungal infection is suspected for a skin condition?

A
  • Skin scraping
  • Nail clipping
  • Hair sample
  • Fungal cultures
42
Q

What is a simple way to take a skin biopsy?

A

Punch biopsy