Introduction to Dermatology Flashcards

1
Q

What is the largest organ in the body?

A

Skin

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2
Q

What are some skin adnexal structures?

A

Hair

Nails

Glands

Sensory structures

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3
Q

What are important functions of the skin?

A
  • Protection
  • Homeostasis
  • Transmission of sensation
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4
Q

What are the layers of the skin from superficial to deep?

A

Epidermis

Dermis

(then below but not part of the skin is the hypodermis)

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5
Q

What are the 5 layers of the epidermis ?

A

1- Stratum corneum-

2- Stratum lucidum

3- Stratum granulosum

4- Stratum spinosum

5- Stratum basale

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6
Q

What are the 3 different stages of the hair cycle?

A

1- Anagen

2- Catagen

3- Telogen

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7
Q

What is the anagen phase of hair cycle?

A

Active growing phase

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8
Q

What is the catagen phase of hair cycle?

A

lasts for 2-3 week,

is the dying phase where hair growth stops

and

follicles shrink

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9
Q

What is the telogen phase of hair cycle?

A

Is resting phase and lasts for 1-4 months

this is the shedding phase

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10
Q

How long does the telogen phase of hair cycle last?

A

1-4 months

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11
Q

How long does the catagen phase of hair growth last?

A

2-3 weeks

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12
Q

During what phase of the hair cycle is most hair grow?

A

Anagen (80-90% hair) the fastest phase

Telogen (up to 10% of hair)

Categen (1-3% of hair) the slowest phase

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13
Q

What are the six functions of the skin?

“important to know this, is a common exam question”

A
  • Thermoregulation
    • Insulation, heat transfer
  • Skin immune system
    • Innate and adaptive functions
  • Barrier
    • Protects against mechanical, chemical, microorganisms, UV light
    • Keep in water and electrolytes, macromolecules
  • Sensation
    • Temperature, touch and pain
  • Vitamin D synthesis
    • UV light converts 7-dehydrocholesterol to cholecalciferol
  • Interpersonal communication
    • Physical appearance, smell, self-identity
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14
Q

How much of skin disease is skin cancer/lesions?

A

50%

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15
Q

Why is skin disease important?

A
  • Disfigurement
  • Discomfort
  • Disability
  • Depression
  • Death
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16
Q

What are some causes of skin disease?

A
  • External
    • Temperature
      • Cold injury
        • Frostbite, chilblains
        • Skin necrosis
        • Cold urticaria
    • UV
      • Called photosensitivity
      • Commonly caused by medications
      • Exposed sites affected
      • Can be sensitive to UVA, UVB, visible light or a combination
    • Chemical
    • Infection (allergen or irritant)
    • Trauma
      • Dermatitis artefacta (skin lesions solely produced by patients own actions)
  • Internal
    • Systemic disease
    • Genetics
    • Drugs
      • Think of OTC drugs
    • Infection
    • Autoimmune
      • Bullous pemphigoid
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17
Q

What are chilblains?

A

Small lesions caused by inflammation of small blood vessels due to exposure to cold air

18
Q

What is cold urticaria?

A

is a skin reaction to cold that appears within minutes after cold exposure

19
Q

What is a skin lesion solely produced by patients own actions called?

A

Dermatitis artefacta

20
Q

What is an example of an autoimmune skin disease?

A

Bullous pemphigoid

21
Q

What is the morphology of a skin lesion?

A

Appearance of a skin lesion

22
Q

How big is a “small” skin lesion?

A

Typically means less than 5mm

23
Q

What are some descriptive words for skin lesions?

A
  • Macule
    • Small circumscribed area
  • Patch
    • Larger circumscribed area
  • Papule
    • Small raised area
  • Plaque
    • Larger raised area
  • Vesicle
    • Small fluid filled
  • Bulla
    • Large fluid filled
  • Pustule
    • Small pus filled
  • Abscess
    • Large pus filled
  • Erosion
    • Loss of epidermis
  • Ulcer
    • Loss of epidermis and dermis
24
Q

What is a macule?

A

1- Small flat circumscribed area

2- Non-palpable, change in skin color, with distinct borders

25
What is a patch?
Larger flat circumscribed area Non-palpable, change in skin color, with distinct borders
26
What is a papule? " paa-pi-yuul"
Small raised area it is Palpable solid lesion, with less than 1 cm in diameter
27
What is a plaque? " ba-laa-Q"
Larger raised area it is Palpable solid lesion, with greater than 1cm in diameter
28
What is a vesicle?
Small fluid filled lesion, superficial with thin walls and less than 1cm diameter.
29
What is a bulla? " bu-la"
Large fluid filled lesion, superficial, with thin walls and greater than 1 cm in diameter.
30
What is a pustule? " Pas-je-yuul"
Small pus filled lesion, superficial with thin walls. Picture shows acne in the background and Pustule
31
What is an abscess?
Large pus filled lesion, with thick wall
32
What is an erosion?
Loss of epidermis only
33
What is an ulcer?
Loss of epidermis and dermis
34
What are some examples of common skin conditions?
35
What are some examples of skin conditions that can have cutaneous signs?
* Erythema nodosum * Sarcoidosis * Vasculitis * Malignancy * Auto-immune conditions
36
What is a skin sign of hyperlipidaemia?
Eruptive xanthoma
37
What is Acanthosis Nigricans?
Brown to black, poorly defined, velvety hyperpigmentation of the skin Hyperkeratosis and hyperpigmentation
38
What is acanthosis nigricans associated with?
Associated with insulin resistance, obesity and malignancy.
39
What investigations should be done if bacterial infection is suspected for a skin condition?
* Charcoal swab * Ask for MC&S * Microscopy * Culture * Sensitivities
40
What investigations should be done if viral infection is suspected for a skin condition?
* Viral swab for PCR * Can swab vesicle/bulla if vesicular eruption * If systemic illness, can take throat swab
41
What investigations should be done if **Fungal** infection is suspected for a skin condition?
* Skin scraping * Nail clipping * Hair sample * Fungal cultures
42
What is a simple way to take a skin biopsy?
Punch biopsy