Introduction to Blood Disorders Flashcards
what are the functions of the blood
transport of nutrients, removal of waste, transport host defences
what does the blood need to carry out their functions?
ability to carry nutrients/waste/defences, ability to self repair
what are the constituents of blood?
cell component, plasma proteins, lipids, nutrients, water
what are the two types of plasma proteints?
albumins and globulins
what is FBC
full blood count
what is RBC
red blood cells
what is WCC
white cell count
what is PLT
platelets
what is HCT
haematocrit
what is MCV
mean cell volume
what is anaemia
low Hb
what is leukopenia
low WCC
what is thrombocytopenia
low platelets
what is pancytopenia
all cells reduced
if there is a reduction of one component in the blood what does this mean?
reactive change to the environment
if there are multiple reductions of components in the blood what does this mean?
bone marrow failure
what is polycythaemia
raised Hb
what is leukocytosis
raised WCC
what is thrombocythaemia
raised platelets
if there is an increase in one of the blood components what does this mean?
reactive or pre-neoplastic
if there is an increase in multiple blood components what does this mean?
pre-neoplastic (myelodysplasia)
what is leukaemia
neoplastic proliferation of white cells usually disseminated
what is lymphoma
neoplastic proliferation of white cells usually a solid tumour
what happens if cells turn neoplastic earlier in the haematological cell line?
the malignancy is more aggressive
