Introduction to Blood Disorders Flashcards

1
Q

what are the functions of the blood

A

transport of nutrients, removal of waste, transport host defences

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2
Q

what does the blood need to carry out their functions?

A

ability to carry nutrients/waste/defences, ability to self repair

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3
Q

what are the constituents of blood?

A

cell component, plasma proteins, lipids, nutrients, water

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4
Q

what are the two types of plasma proteints?

A

albumins and globulins

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5
Q

what is FBC

A

full blood count

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6
Q

what is RBC

A

red blood cells

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7
Q

what is WCC

A

white cell count

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8
Q

what is PLT

A

platelets

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9
Q

what is HCT

A

haematocrit

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10
Q

what is MCV

A

mean cell volume

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11
Q

what is anaemia

A

low Hb

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12
Q

what is leukopenia

A

low WCC

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13
Q

what is thrombocytopenia

A

low platelets

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14
Q

what is pancytopenia

A

all cells reduced

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15
Q

if there is a reduction of one component in the blood what does this mean?

A

reactive change to the environment

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16
Q

if there are multiple reductions of components in the blood what does this mean?

A

bone marrow failure

17
Q

what is polycythaemia

A

raised Hb

18
Q

what is leukocytosis

A

raised WCC

19
Q

what is thrombocythaemia

A

raised platelets

20
Q

if there is an increase in one of the blood components what does this mean?

A

reactive or pre-neoplastic

21
Q

if there is an increase in multiple blood components what does this mean?

A

pre-neoplastic (myelodysplasia)

22
Q

what is leukaemia

A

neoplastic proliferation of white cells usually disseminated

23
Q

what is lymphoma

A

neoplastic proliferation of white cells usually a solid tumour

24
Q

what happens if cells turn neoplastic earlier in the haematological cell line?

A

the malignancy is more aggressive

25
Q

what is porphyria?

A

abnormality of haem metabolism

26
Q

what dental aspect triggers porphyria?

A

LA

27
Q

what are the clinical effects of porphyria?

A

photosensitive rash, neuropsychiatric disturbance in acute attacks, hypertension and tachycardia