Introduction To Biochemistry Flashcards
What enzyme is responsible for the increased sensitivity to alcohol of some people?
Aldehyde dehydrogenase
If there is a defect in aldehyde dehydrogenase what will happen?
There will be accumulation of acetaldehyde. > Increased acetaldehyde level in blood > inc sensitivity to alcohol > less ethanol req for vasodilation > facial flushing and inc heart rate
Aspirin interferes with the production of _______ and _________ from arachidonate (cyclooxygenase enzyme) to prevent heart attack.
Prostaglandins; Thromboxanes
This functions to transport fatty acids to the mitochondria where oxidation of fatty acids takes place.
Carnitine
True or False: Carnitine helps in fat metabolism.
True
The presence of this compound results in the formation of pheomelanin (reddish-brown pigment).
Glutathione
Holds the cell together and binds certain regulatory substances through its receptors.
Plasma membrane
Repository of genetic information
Nucleus
The site of ribosomal assembly that contain copies of genes for rRNA.
Nucleolus
Complicated array of vesicular spaces separated from the cytosol by a system of membranes.
Endoplasmic reticulum
The RER are lined with ribosomes on what surface?
Cytoplasmic surface
SER found in intestinal cells functions for the synthesis of _______.
Triglycerides
SER found in adrenalcortex cells function in the synthesis of ______.
Steroid hormones
SER found in liver cells is the site of ____________ involved in metabolism of steroids, drugs, etc.
Cytochrome P450
It is the site glycosylation.
Golgi apparatus
It contains the enzymes of kreb’s cycle, beta-oxidation of fatty acids, ETC and oxidative phophorylation.
Mitochondria
Contains hydrolytic and degradative enzymes used to digest foreign materials in the cell.
Lysosomes
This functions to recycle cellular components.
Lysosomes
Microbodies that contain oxidase and catalases.
Peroxisomes