INTRODUCTION TO BIOCHEMISTRY Flashcards
Biochemistry definition
It is the study of
-molecules present in living things.
-Enzyme catalyzed chemical reactions
-Metabolic pathways and how they are regulated
contains all life forms
APPLICATION OF BIOCHEMISTRY
- MEDICINE: Measuring of levels of enzymes in the blood for the diagnosis of diseases.
- AGRICULTURE: Genetic engineering
* DNA is changed by inserting genes from another plant or animal
* increase the yield and quality of the product. Genetically Modified Organisms(GMOs) - BREWING INDUSTRY:use of yeast to ferment glucose found in the grains( Millet , barley, sorghum)
* Glucose is converted to ethyl alcohol.
Metabolism definition
chemical reactions taking place within an organism to maintain life
Include Anabolism and Catabolism
4 Major biomolecules
macromolecules
i. Amino acids and Proteins
ii.Carbohydrates.
iii.Lipids.
iv.Nucleotides and nucleic acids
4 major elements in living organisms are
CARBON, NITROGEN, OXYGEN, HYDROGEN
Definition of functional groups
reactive sites of biological molecules
can participate in chemical reactions and interact with other elements
types of fuctional groups and their structure
- Hydroxyl(-OH): found in alcohols, sugars, and some amino acids.
* It is polar and can form hydrogen bonds with water molecules. - Carbonyl (>C=O): found in aldehydes, ketones, and some amino acids.
* is polar and can participate in reactions that involve the transfer of electrons. - Carboxyl (-COOH): found in organic acids, such as amino acids and fatty acids.
* is acidic and can donate a proton (H+) to other molecules. - Amino (-NH2): found in amino acids, which are the building blocks of proteins.
* is basic and can accept a proton (H+) from other molecules.
5.Phosphate (-PO4): This functional group is found in nucleotides which are the building blocks of DNA and RNA.
* is negatively charged and can participate in reactions that involve the transfer of energy.
6.Ether(R-O-R)
7.Ester
8.anhydride
20 Amino acids and proteins
common 20