Introduction PPT Flashcards

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1
Q

What is Genetics?

A

the study of heredity and variation

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2
Q

Structurally cells are of two basic types. What are they?

A

They are eukaryotic and prokaryotic

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3
Q

What is the fundamental unit of heredity?

A

The fundamental unit of heredity is the gene

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4
Q

Genetic information is carried in the macromolecules called?

A

DNA and RNA

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5
Q

Where the genes are located?

A

Genes are located on chromosomes

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6
Q

What is the Central Dogma of Biology?

A

Central Dogma of Biology states genetic info is transferred from
DNA-> mRNA -> protein

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7
Q

Difference between genetic make up of an organism vs physical expression

A

Genotype vs Phenotype

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8
Q

What is the fundamental macromolecule of DNA?

A

nucleic acid (deoxyribonucleic acid)

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9
Q

DNA is composed of subunits called

A

Nucleotides

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10
Q

DNA nucleotide consists of 3 parts?

A

(1) phosphate group
(2) pentose sugar —-> deoxyribose (name)
(3) nitrogenous base (adenine, cytosine, guanine, or thymine)

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11
Q

What is the sugar phosphate backbone of DNA?

A

It’s the sugar phosphate backbone, which connects one nucleotide of deoxyribose sugar and phosphate group to another nucleotide in the row

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12
Q

What are the Nitrogenous (N) bases of DNA?

A

They are Adenine (A), Thymine (T), Guanine (G) and Cytosine (C)

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13
Q

What is the meaning of antiparallel strand?

A

When strands are antiparallel, it means that they run in opposite directions 5’ – 3’ strand and 3’ – 5’ strand.

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14
Q

What is the meaning of complementary strand in DNA?

A

The complementary strand in DNA means that A = T and C = G (complementary base pairing).

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15
Q

How the base pairs are connected to each other?

A

The base pairs are connected to each other with the help of

Hydrogen bonding.

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16
Q

How many H bonds do we have A = T vs C = G for DNA

A

We have 2 hydrogen bonds for A = T and 3 hydrogen bonds C = G
in DNA.

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17
Q

What are the purines?

A

The purines are Adenine and Guanine with 2 rings

18
Q

What are the pyrimidines?

A
The pyrimidines are the one rings: Cytosine and Thymine (in DNA); 
and Uracil (in RNA)
19
Q

Different versions of genes are called

A

Alleles.

20
Q

What is the nucleotide of RNA?

A

(1) phosphate group
(2) pentose sugar (ribose)
(3) nitrogenous base, but Uracil replaces Thymine

21
Q

Proteins are made of? (continue on my own)

A

Proteins are made of amino acids

22
Q

What is the general structure of amino acid? (Hint: 3 parts)

A

(1) amino group
(2) carboxyl group
(3) side chain

23
Q

The side chain determines what?

A

The chemical properties of amino acid

24
Q

The protein is made up of?

A

20 different amino acids

25
Q

The order of amino acids determines what?

A

The order of amino acids determines the type of protein and its 3D structure

26
Q

What are the levels of protein structure?

A

primary s-re, secondary s-re, tertiary s-re and quaternary s-re

27
Q

DNA packed into chromosomes found in?

A

The nucleus

28
Q

How is DNA condensed?

A

In humans, DNA condensed using histone proteins and chromatin.
This means that histone proteins take the DNA and wrap it up, decreasing the length of DNA.

29
Q

What is the genome?

A

Genome is the entire set of chromosomes in each cell of an organism

30
Q

What are the homologous chromosomes (homologs)?

A

Homologs are chromosomes that contain the same set of genes, but have different alleles for some genes

31
Q

What is biparental inheritance?

A

Biparental inheritance is a type of inheritance where the progeny inherits a maternal and a paternal allele for one gene. The progeny gets 23 chromosomes from each parent, which is total 46 chromosomes.

32
Q

Cell division that maintains chromosome number is termed?

A

Mitosis

33
Q

Cell division that decreases chromosome number by half is termed?

A

Meiosis

34
Q

Haploid vs Diploid

A

Haploid - State of a cell with one copy of each chromosome. Human gametes have one copy of 23 chromosomes.
Diploid - State of a cell with 2 copies of homologous chromosomes, which is total 46 chromosomes.

35
Q

What is loci (locus)

A

Loci (locus) is the specific location of the gene

36
Q

What is karyotype?

A

the number and visual appearance of the chromosomes in the cell nuclei of an organism

37
Q

What is Transmission genetics?

A

studies basic principles of heredity- how traits are passed from one generation to the next.
-Focus- individual organism

38
Q

What is the Molecular genetics?

A

It’s the chemical nature of the gene itself. Replication, transcription and translation, gene regulation

39
Q

What is Population genetics?

A

Population genetics - explores the genetic composition of groups of indiv. members of same species and
how that changes over time and space.

40
Q

Genes vs Allele difference

A

Genes determine the letter from the alphabet. But the allele specifies whether the letter is uppercase (A) or lowercase (a)

41
Q

Haploid

A

an organism or cell having only one complete set of chromosomes (1n)

42
Q

Diploid

A

an organism or cell having two sets of chromosomes or twice the haploid number (2n)