Introduction and Prescriptions Flashcards
Define pharmacology
study of agents used to treat, diagnose, and prevent disease
what are the two major divisions of pharmacology
pharmacodynamics
pharmokinetics
define pharmacodynamics
what the drug does to the body
biochemical and physiological mechanism
define pharmokinetics
what the body does to the drug
absorption, distribution, metabolism, elimination
what are two groups drugs can be put into?
Give examples for each group
affecting the patient - ANS, cardiac, coagulation, renal, endocrine etc.
affecting parasites - antibiotics, anti-fungals, anti-worm agents, etc.
what is another way of classifying drugs in regard to the drug itself? (3 groups)
OTC drugs
Prescription/Legend drugs
Vaccines and Biologics
what is the central philosophy of drug regulation for animals use
- Protect the public from inadvertent consumption of harmful amounts of drugs given to livestock
- Allow livestock producers to protect the animal’s health with minimal oversight
what are the defined parameters of a labeled use drug?
dose, frequency, duration, route of administration, species, treat specific disease
when can a drug be sold without a prescription?
when the parameters of a labeled drug can be understood by a lay person
what kind of drugs are OTC
labeled use
when is a prescription required?
- labeled use not understood by lay person
- professional needed to diagnose disease and monitor response to drug or adverse effects
what is ELDU
extra label drug use - use of drug in someway other than the label
what is a drug that is used without a label called
extra label drug use
what does labeled use apply to
OTC and prescription drugs
what made ELDU illegal in 1958?
FD&CA
what made ELDU legal in 1994?
animal medicinal drug use clarification act (AMDUCA)
what are the conditions of AMDUCA?
- must adhere to label use unless judged to be ineffective
- ELDU only allowed for FDA approved drugs
- human drug cant be used if animal drug can be used
- requires veterinary supervision and VPCR
- cant be administered in food but can be in water
what is the color of the FDA human and animal drug book?
human - orange
animal - green
what are the AMDUCA conditions for food animals?
- only for therapeutic use, not production
- can’t result in any tissue residue thats a risk to public health
- absence of scientific data on human food safety the animal must be kept out of food supply
what is an OTC drug that is used in a way it is not labeled?
ELDU - consider prescribing