Introduction Flashcards

Makapasa sa Sem2

1
Q

A substance that stimulates antibody formation and has the ability to bind to an antibody

A

Antigens

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2
Q

A LMW, non-antigenic substance that, when combined with an antigen, changes the antigenic specificity of that antigen

A

Hapten

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3
Q

A glycoprotein substance that is produced by lymphocytes in response to an antigen

A

Antibody

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4
Q

Derived from a single B-cell clone and are produced as a single class of immunoglobulin with specificity unique to the antigenic stimulus

A

Monoclonal antibodies

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5
Q

Produced as different classes of immunoglobulins by many B-cell clones in response to an antigen

A

Polyclonal Antibodies

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6
Q

The part of an antigen that reacts specifically with an antibody or T-cell receptor

A

Epitope

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7
Q

Clumping of particulate antigens by antibodies specific for the antigen

A

Agglutination

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8
Q

The tendency for combining with the antigen-binding site on an antibody molecule

A

Affinity

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9
Q

The strength of the bond between the antigen and the antibody

A

Avidity

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10
Q

The smallest amount of antigen or antibody that can be detected

A

Sensitivity

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11
Q

The ability of an antibody to bind to an antigen with complementary determinants

A

Specificity

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12
Q

Glycoprotein substances secreted by antigen-stimulated B cell

A

Immunoglobulin

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13
Q

Exist as monomer in serum and as a dimer in body secretions

A

IgA

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14
Q

Serum levels

77-400mg/dl

A

IgA

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15
Q

Serum levels

3-5

A

IgD

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16
Q

Serum levels

17 - 450

A

IgE

17
Q

Serum levels

591 - 1965

A

IgG

18
Q

Serum levels

50 - 311

A

IgM

19
Q

Small fragments which attracts and activate different types of leukocytes. It is activated whenever there is an allergen

A

Anaphylotoxins

20
Q

3 cluster differentiation

A

CD68 - MACROPHAGES
CD69 - ACTIVATED LYMPHOCYTES
CD70 - REED STERNBERG CELL

21
Q

Gene Product

HLA-A
HLA-B
HLA-C

A

Class 1 MHC

22
Q

Gene Products

HLA-DP
HLA-DQ
HLA-DR

A

Class 2 MHC

23
Q

Gene Products

Complemen
TNF
Heat shock protein

A

Class 3 MHC

24
Q

Ag specificity of Class 1 MHC

A

8-10 amino acid

25
Q

Ag specificity Class 2 MHC

A

13-18 amino acid

26
Q

MHC antigen presentation of Class 1

A

CD8 T-Cells

27
Q

MHC antigen presentation of Class 2

A

CD4 T-cells

28
Q

Endogenous

Cellular location of recognition

A

MHC-1

29
Q

Exogenous

Cellular location of recognition

A

MHC-2

30
Q

Type 1 hypersensitivity reaction

A

Urticaria
Hay fever
Bronchial asthma