Introduction

Question 1

A substance that stimulates antibody formation and has the ability to bind to an antibody

Answer 1

Antigens

Question 2

A LMW, non-antigenic substance that, when combined with an antigen, changes the antigenic specificity of that antigen

Answer 2

Hapten

Question 3

A glycoprotein substance that is produced by lymphocytes in response to an antigen

Answer 3

Antibody

Question 4

Derived from a single B-cell clone and are produced as a single class of immunoglobulin with specificity unique to the antigenic stimulus

Answer 4

Monoclonal antibodies

Question 5

Produced as different classes of immunoglobulins by many B-cell clones in response to an antigen

Answer 5

Polyclonal Antibodies

Question 6

The part of an antigen that reacts specifically with an antibody or T-cell receptor

Answer 6

Epitope

Question 7

Clumping of particulate antigens by antibodies specific for the antigen

Answer 7

Agglutination

Question 8

The tendency for combining with the antigen-binding site on an antibody molecule

Answer 8

Affinity

Question 9

The strength of the bond between the antigen and the antibody

Answer 9

Avidity

Question 10

The smallest amount of antigen or antibody that can be detected

Answer 10

Sensitivity

Question 11

The ability of an antibody to bind to an antigen with complementary determinants

Answer 11

Specificity

Question 12

Glycoprotein substances secreted by antigen-stimulated B cell

Answer 12

Immunoglobulin

Question 13

Exist as monomer in serum and as a dimer in body secretions

Answer 13

IgA

Question 14

Serum levels

77-400mg/dl

Answer 14

IgA

Question 15

Serum levels

3-5

Answer 15

IgD

Question 16

Serum levels

17 - 450

Answer 16

IgE

Question 17

Serum levels

591 - 1965

Answer 17

IgG

Question 18

Serum levels

50 - 311

Answer 18

IgM

Question 19

Small fragments which attracts and activate different types of leukocytes. It is activated whenever there is an allergen

Answer 19

Anaphylotoxins

Question 20

3 cluster differentiation

Answer 20

CD68 - MACROPHAGES
CD69 - ACTIVATED LYMPHOCYTES
CD70 - REED STERNBERG CELL

Question 21

Gene Product

HLA-A
HLA-B
HLA-C

Answer 21

Class 1 MHC

Question 22

Gene Products

HLA-DP
HLA-DQ
HLA-DR

Answer 22

Class 2 MHC

Question 23

Gene Products

Complemen
TNF
Heat shock protein

Answer 23

Class 3 MHC

Question 24

Ag specificity of Class 1 MHC

Answer 24

8-10 amino acid

Question 25

Ag specificity Class 2 MHC

Answer 25

13-18 amino acid

Question 26

MHC antigen presentation of Class 1

Answer 26

CD8 T-Cells

Question 27

MHC antigen presentation of Class 2

Answer 27

CD4 T-cells

Question 28

Endogenous

Cellular location of recognition

Answer 28

MHC-1

Question 29

Exogenous

Cellular location of recognition

Answer 29

MHC-2

Question 30

Type 1 hypersensitivity reaction

Answer 30

Urticaria
Hay fever
Bronchial asthma