Introduction Flashcards

1
Q

Epidemiology

A

Study of distribution and determinants of health related conditions in human populations and the application of this method to the control of health problems.
Considers measuring who has the disease and who has exposure.

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2
Q

Benefits of epidemiology

A

Description of health status of populations explanation of the aetiology of disease
Predict the likely occurrence of disease/ health and identify distribution in the population
Control occurrence of disease

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3
Q

Use of epidemiology

A

Can be used to describe both healthy and unhealthy populations- described demographically
Track trends
Establish risk factors
Determines the health of a community

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4
Q

Epidemiology and research

A

Monitors the health status of a population and searches for risk factors

After a hypothesis is developed, provide descriptive analysis of a problem. Conduct a study to test hypothesis.

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5
Q

Steps used to construct epidemiological research

A
Determine primary agent 
Understand causation 
Determine characteristics of agent 
Determine mode of transmission 
Determine contributing factors 
Assess geographic patterns 
Define natural history 
Determine control measures
Determine prevention measures 
Planning health services 
Determine hypothesis
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6
Q

Epidemic

A

A disease or condition that affects a greater than expected number of individuals at the same time
Normal occurrence of disease in a pop is known as endemic level.
Epidemic threshold is the upper end of normal range of disease occurrence for a specific population, time frame and location

A pandemic is a geographically widespread epidemic

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7
Q

Stages of clinical disease

A

Nonclinical : preclinical where signs and symptoms are not yet present, subclinical where symptoms will not become apparent

Recovery 
Morbidity
Disability 
Mortality
Carrier state

Most diseases not identified until in clinical stage, must take note of stage of disease

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8
Q

Epidemiological triangle

A

Composed of:
Agent- what causes the disease
Host- personal characteristics of those affected by the disease
Environment- external factors that cause or allow disease to be spread

Time ties into triangle elements, crucial to understanding disease transmission

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9
Q

Agent component of the triangle

A

Agents of infectious diseases are microbes: viruses and bacteria

Agents for non infevtuous disease are risk factors such a as smoking, high bp, and exposure to chemicals or radiations

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10
Q

Host component of triangle

A

Organisms that are exposed to and Harbour a disease
Can be the organism who gets sick, an organism that transmits an infection but may or may not get sick.
Different hosts ah have different reactions to the same agent.
Host characteristics may affect disease susceptibility:
Age
Gender
Race
Occupation
Immune status
Behaviours

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11
Q

Environment component of triangle

A

External conditions that cause/ allow disease transmission
Some disease live best in dirty water
Others survive in human blood
Others thrive in warm temp but are killed by high heat
Environmental characteristics shown to promote disease include
Weather
Population density
Geography
Seasonality

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12
Q

Time - centre of triangle

A

Incubation persons- time between infection of host and symptoms appear
Called latency period for chronic disease. Can be hours, days, weeks.
Time amy also describe duration of disease or amount of time a person is sick before death or recovery occurs.

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13
Q

Epidemiology mission

A

To break the triangle by understanding cause of disease, groups likely to get the disease and geographical factors conductive of the spread

Breaking the triangle- avoid exposure or immunise against the agent
Address the environmental issue by isolating people with certain disease
Control risk factors for chronic disease

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14
Q

Disease occurrence- descriptive epidemiology of person

A

The field of medicine deals with one person at a time while epidemiology deals with groups

Who gets the condition?

  • how old
  • where do they live
  • where do they work?
  • where were they born
  • what sort of people do not get the disease?
  • how many cases per 100,000

Does this rate differ between

  • men and women
  • young and old
  • rich and poor
  • black and white
  • Heterosexual and homosexual
  • migrants and locally born
  • different occupations
  • married or not
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15
Q

Disease occurrence- descriptive epidemiology of place

A
Where does this disease happen? 
Is it more common in some place? 
Does the rate differ between: 
Countries
States
Rural and urban 
Suburbs
Communities
Households
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16
Q

Disease occurrence- descriptive epidemiology of time

A

Could apply to seasonal patterns
Could refer to trends over time
Can be important in assessing unusual increases or decreases
Can help identify an epidemic or disease that occurs at a greater than expected frequency
When does this disease happen?
How many cases occur per year in the population? How does this rate change? Is it increasing? Is it seasonal? Is there a pattern in the rate?

Variations typically observed:
Time of day
Day of week
Season

17
Q

Secular (long term trends)

A

Changes in diagnostic testing
Changes in disease detection
Changes in disease classification
Rise or falling exposure to a cause or disease
Reporting bias eg coding of adverse events or complications in hospital
Changes in age distribution
Changes in survival from disease due to improved treatments

18
Q

Exposure occurrence in EPI studies

A

First depends on identifying the characteristics classified as exposures and criteria for measurements should be made before beginning data collection
Many investigators forget to develop clear and consistent definitions for heir exposure variables
If exposure variable or risk factors are not counted correctly, results can be questionable or wrong

19
Q

Causality

A

Cause refers to something that brings about an effect or result
Direct- clear which factors cause the problem without any intermediate steps
Indirect cause- a factor that may cause a problem but with an intermediate factor or step

20
Q

Levels of prevention

A

Primary- preventing diseases from occurring at all
Secondary- diagnosing diseases in early stages where treatment or lifestyle changes can divert the natural disease course
Tertiary- preventing further complications and disability