Introduction Flashcards

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1
Q

gene

A
  • functional unit of heredity
  • needed to synthesis RNA molecules
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2
Q

chromosome

A
  • combo of DNA and protiens
  • uniploid (single) or polyploid ( > one)
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3
Q

gene expresssion

A
  • process where info from gene is converted into observable product
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4
Q

mutation

A
  • transmissible permanant change
  • can change or alter function
  • lethal = death
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5
Q

genome

A
  • all genes from a single gamete
  • complete set of genomic info
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6
Q

genotype

A
  • all genes of an organism
  • can also mean the alleles at specific loci
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7
Q

phenotype

A
  • physical appearance due to genotype and environment
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8
Q

alleles

A
  • alternating forms of a single gene (ex, hair colour)
  • can differ by only one base
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9
Q

biochemical approach

A
  • going from proteins that are being isolated by their function or activity and then going toward the DNA
  • activity can be looked at in different condition
  • the goal is to deduce the nucleotide sequence of the gene
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10
Q

genetic approach

A
  • starting at the gene, looking at mutated DNA vs. normal, and going toward the proteins
  • allows us to understand what the importance of a protein is, how many genes are involved, the order of the genes (complementation analysis) and the interactions of those genes (genetic suppression)
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11
Q

bioinformatics

A
  • using computer science to answer biology questions
  • compilations of molecular data in databases
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12
Q

model organisms

A
  • small, simple, cheap, easy to maintain, short reproductive cycle, lots fo research on them
  • studies are simplified due to them being less-complex organisms
  • ex. E.coli, yeast, drosophila, zebrafish, frogs, plants, mouse/rat
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13
Q

reporter gene

A
  • coding region joined to a promoter sequence that is introduced into cells to provide the means for measuring the promoter activity.
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14
Q

transgenic organism

A
  • an organism that has foreign DNA introduced into one or more of its cells artificially
  • can be integrated in a random or controlled fashion
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15
Q

knockout organism

A
  • DNA is introduced into the cell at a targeted, specific place to knock out the turning on of a gene
  • still considered transgenic as you are inserting DNA into a cell
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