Introduction Flashcards
1
Q
gene
A
- functional unit of heredity
- needed to synthesis RNA molecules
2
Q
chromosome
A
- combo of DNA and protiens
- uniploid (single) or polyploid ( > one)
3
Q
gene expresssion
A
- process where info from gene is converted into observable product
4
Q
mutation
A
- transmissible permanant change
- can change or alter function
- lethal = death
5
Q
genome
A
- all genes from a single gamete
- complete set of genomic info
6
Q
genotype
A
- all genes of an organism
- can also mean the alleles at specific loci
7
Q
phenotype
A
- physical appearance due to genotype and environment
8
Q
alleles
A
- alternating forms of a single gene (ex, hair colour)
- can differ by only one base
9
Q
biochemical approach
A
- going from proteins that are being isolated by their function or activity and then going toward the DNA
- activity can be looked at in different condition
- the goal is to deduce the nucleotide sequence of the gene
10
Q
genetic approach
A
- starting at the gene, looking at mutated DNA vs. normal, and going toward the proteins
- allows us to understand what the importance of a protein is, how many genes are involved, the order of the genes (complementation analysis) and the interactions of those genes (genetic suppression)
11
Q
bioinformatics
A
- using computer science to answer biology questions
- compilations of molecular data in databases
12
Q
model organisms
A
- small, simple, cheap, easy to maintain, short reproductive cycle, lots fo research on them
- studies are simplified due to them being less-complex organisms
- ex. E.coli, yeast, drosophila, zebrafish, frogs, plants, mouse/rat
13
Q
reporter gene
A
- coding region joined to a promoter sequence that is introduced into cells to provide the means for measuring the promoter activity.
14
Q
transgenic organism
A
- an organism that has foreign DNA introduced into one or more of its cells artificially
- can be integrated in a random or controlled fashion
15
Q
knockout organism
A
- DNA is introduced into the cell at a targeted, specific place to knock out the turning on of a gene
- still considered transgenic as you are inserting DNA into a cell