Introduction Flashcards

1
Q

defined molecular biology as the study of dna

A

james watson

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2
Q

head of the natural science division of the rockfeller foundation

A

warren weaver

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3
Q

first to use the term molecular biology

A

warren weaver

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4
Q

deals with molecular techniques for handling and analysis of nucleic acids

A

diagnostic molecular biology

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5
Q

discovered dna and extracted nuclein

A

john friedrich miescher

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6
Q

first to demonstrate bacterial transformation

A

frederick griffith

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7
Q

type s

A

virulent

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8
Q

type r

A

non virulent

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9
Q

implicated that DNA is responsible for bacterial transformation

A

avery, macleod, mccarty

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10
Q

enzyme that digest proteins

A

proteases

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11
Q

enzymes that breaks apart RNA

A

ribonucleases

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12
Q

enzymes that act on DNA

A

DNases

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13
Q

took the photo 51

A

rosalind franklin & raymond gosling

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14
Q

studies of DNA’s structure through X-ray diffraction

A

(X-ray crystallography)

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15
Q

helped confirmed that DNA is the genetic material by performing experiments

A

alfred hershey and martha chase

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16
Q

performed chromatographic methods about adenine, thymine, guanine, cytosine

A

erwin chargaff

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17
Q

adenine is equal to

18
Q

guanine is equal to

19
Q

published in nature, the first correct model of the DNA molecule

A

james watson and francis crick

20
Q

utilized franklin’s “photo 51”

A

james watson and francis crick

21
Q

they performed the first known successful DNA recombinant experiment

A

herbert boyer and stanley norman cohen

22
Q

seperately developed techniques for rapid DNA sequencing

A

walter gilbert and frederick sanger

23
Q

invented the pcr technique

A

kary mullis

24
Q

presented the zinc finger nucleases

A

nikola panayot pavletich and carl pabo

25
Q

first to generate the mammalian clone, dolly the sheep

A

sir ian wilmut

26
Q

a roundworm who became the first multicellular organism to have its entire genome decoded

A

caenorhabditis elegans

27
Q

first crop to have its entire genum decoded

28
Q

this project completely mapped and identified all of the genes of the human genome

A

human genome project

29
Q

enzymes that can be engineered to cut specific dna sequences

30
Q

meaning of talens

A

transcription activator-like effector nucleases

31
Q

utilized for genome editing purposes

A

crispr-cas9

32
Q

meaning of crispr

A

clustered regularly interspaced short palindromic repeats

33
Q

refers to the analysis of nucleic acids and proteins for diagnosis

A

molecular pathology

34
Q

PREDICT disease progression

35
Q

DETECT normal and disease states

36
Q

identifying the gene expression pattern

A

redefinition of diseases

37
Q

molecular biology enabled clinicians to identify genes that have the potential of causing cancer

A

detection of cancer

38
Q

molecular techniques have enabled the detection of pathogens

A

detection of infectious diseases

39
Q

genetic screeing for the presence of proteins involved in drug metabolism

A

treatment of diseases

40
Q

studies how drug responses occur concerning an individual’s genome

A

pharmacogenomics and personalized medicine

41
Q

diagnostic molecular techniques have been of great assistance for predicting the manifestation of genetic diseases

A

diagnostic of genetic diseases