Introduction

Question 1

Disease

Answer 1

set of features (signs, symptoms, morphological and functional manifestations)

Question 2

Systematic description

Answer 2

epidemiology, cause, pathogenesis (disease mechanism), symptoms, manifestations, complications and sequelae, prognosis, mortality

Question 3

Terminology

Answer 3

Prefixes (hyper, meta, hypo, etc)
Suffixes (itis, oma, oid, etc)
Eponyms: Crohn’s disease

Question 4

Diagnoses based on

Answer 4

Histology (biopsy, resection, frozen section)
Cytology (fine needle aspirations (lymph node), brushes (biliary tract), fluids (ascitis, pleural fluid), smears (uterine cervix), urine, liquor)
Additional: obtain as much info as possible from cells and tissues (molecular diagnosistics)

Question 5

Cassets

Answer 5

Little boxes to store preparations
Tissue fixation (formalin), dehydration, embedding, paraffin blocks, cutting, slice, (H&E sections), evaluation