Introduction Flashcards
Phineas Gage
1823-1860; Field: neurobiology; Contributions: 1st person to have a frontal lobotomy (by accident), his accident gave information on the brain and which parts are involved with emotional reasoning
Henry Molaison (H.M.)
famous patient who suffered anterograde amnesia (cannot form new memories) after having surgery – but remembered implicit memories (getting shocked with hand)
HM after surgery
was cured: no more seizures: normal intelligence, cooperative and motivated, normal perceptual and reasoning skills
BUT - unable to form new long-term memories
anti localization
brain working together as a whole
localization
brain working in separate parts
in vivo
in a life or within their biological system
“seat of mind”
refers to the mind
dualism theory
the mind and brain are two different substances
dual-aspect theory
states that the mind and bran are the same thing
mass action (jean flourens)
made small lesions in birds and decided that the entire brain is one single function
Broca’s
Tan –> language
Gall & Spurzheim
- First to hypothesize localization of function
- The more you use some function → the more neural resources you have dedicated to that function
Carl Wernicke
- Patients have no issues with producing language, but never make sense when speaking
(also can’t read and have no comprehension) - Shows that one part of the brain is responsible for saying language, and the other
for stringing it together
Golgi
- Invents a silver nitrate staining method using syncytium (a common cytoplasm)
- Uses his stain to label the composition of the brain and sees one whole part of the brain
Cajal
- Discovers brain is made up of individual units; uses Golgi’s stain to do the same thing but
sees little gaps in between individual cells (so not a single net) - Discovers neurons are discrete cells that signal transmission