Intro to Pulmonary Diagnostics Flashcards
Pulmonary mechanics of inspiration
Intercostal muscles and diaphragm contract Lungs expand Air drawn in
What is the only artery in the body that carries deoxygenated blood?
Pulmonary artery
Pulmonary mechanics of expiration
Passive process Depends on elastic recoil of lungs
Airway obstruction.
Asthma Chronic bronchitis COPD Results in air trapping due to decreased expiratory flow
Fingernail clubbing
Many causes including -lung cancer -TB -Cystic Fibrosis -Endocarditis
CXR
Common indications -pneumonia -pneumothorax -CHF Noninvasive Low radiation exposure Cost: $200-350
Pulmonary function testing
Spirometry -measures volume and speed of airflow on inspiration and expiration. Used to diagnose and assess asthma, COPD, pulmonary fibrosis Noninvasive, safe
CT scan of the chest
Used to diagnose -PE -pneumonia -aortic dissection -lung cancer Much higher sensitivity than a CXR Higher radiation (100-400X) Higher cost ($1800)
Spiral CT
Continuous, rotating beam Quicker, higher resolution than conventional CT
Multirow CT
Latest generation of CT Thinner slices, improved resolution
CT for PE
CT is the preferred study to assess for PE because it is highly sensitive and non-invasive
With IV contrast
Look for filling filling defects in pulmonary arteries or branches
Will also show alternate causes of sxs
Ventilation/perfusion scan
(V/Q Scan)
Also used to asses for PE when important to reduce radiation exposure or when contrast can’t be administered (renal dz/allergy)
Ventilation: radionuclide inhaled to assess ability of air to reach all parts of lungs
Perfusion: IV radionuclide to assess blood circulation
V/Q Mismatch: where normal airflow, but impaired perfusion
Results can be normal, low probability, intermediate probability, or high probability
Low or intermediate probability cannot r/o PE
Pulmonary Angiography
Diagnose PE
Insert catheter under fluoro into pulmonary arteries and inject dye
Invasive, higher risk.
Same sensntivity as CT so has largely been replaced
D-Dimer
Fibrin degredation product released by a clot
Elevated with PE, DVT
If pt has low to moderate risk of PE and has normal D-Dimer, can r/o PE
Very sensitive (95%), but not very specific (50%)
False positives with: inflammation, cancer, pregnancy, advanced age, trauma
Sputum Culture
Used to identify specific organism causing pneumonia
May be contaminated by oral flora
WBC
Often, but not always, elevated with pneumonia
Neither sensitive nor specific