Intro to Pharmacology Flashcards

1
Q

What is a therapeutic Class

A

It tells you about condition(s) that the drug acts on. About tis clinical uses.

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2
Q

What is a phrmocologic class

A

It tells you about the mechanism of action of the drug

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3
Q

What is a trade name

A

The bran name of the drug such as Advil

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4
Q

Which type of drugs must meet USP standards?

A

Prescription and over the counter drugs

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5
Q

Which agency enforces the controlled substances act

A

The DEA

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6
Q

What is included in the pharmaceutical phase of taking a drug? What is the next phase?

A

Disintegration and Disolution?

It is followed by absorption. The first phase of pharmokinetics.

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7
Q

What are the three broad phases taking a drug?

A

Pharmoacological Phase, Pharmocokinetics, and pharmacodynamics.

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8
Q

What is pharmacodymaics?

A

The drug action on the bod

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9
Q

What are pharmacokinetics? What are the 4 steps?

A

What the body does to the drug. Absorption, distribution, metabolism, excretion.

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10
Q

Which type of molucules easily cross the cell membrane.

A

not ionized, noon-polar, lipid soluable.

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11
Q

Which molecules have difficulty crossing the cell membrane?

A

ionized, charged, or polar molecules.

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12
Q

What factors affects the absorption of drugs?

A

Surface area, Route of administration, pH or absorptive site, Drug interactions.

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13
Q

What kind of drugs are absorbed in acidic environments? Why?

A

Acid Drugs. It will have a Hydrogen attached in an acid environment and it will not be ionized. It will be better absorbed in a non-ionized state.

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14
Q

Where are alkaline drugs best absorbed?

A

In basic/ alkaline environments.

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15
Q

What is an active metabolite?

A

A drug that is still active its from after it is metabolized.

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16
Q

What two factors and tow drugs we learned about so far lower CYP450 activity? What is the therapturic effect of this?

A

Ages extremes (neo-nates or older adults), Liver disease. Cimetidine, and erythromycin. Lower metabolism will increase the therapeutic effect, and cause increased side effects and possible toxic effects.

17
Q

Which factors or drugs induces CYP450 enzymes?

A

Alcohol, charbroiled food, smoking (including marijuana, and St. John’s Wort.

18
Q

What is the clinical importance of increased CYP450 activity.

A

Increased activity means drugs are metabolize more quickly and can result in lowered therapeutic effect.