Intro To Pharma

Question 1

what constitutes a drug?

Answer 1

A chemical that is administered with the intention of altering the physiology of the body for therapeutic purposes

Question 2

What are the three separate names of a drug?

Answer 2

Generic/approved
Brand/proprietary
Chemical

Question 3

Which of the following makes is which:

• N-methyl-3-phenyl-3-[4-(trifluromethyl)phenoxy]propan-1-amine
• fluoxetine
• Prozac

Answer 3

• chemical
• generic
• brand

Question 4

When classifying a drug what four factors should be mentioned?

Answer 4

Source- where it came from
Chemical name
What it is used to treat
How it works

Question 5

What is pharmacodynamics ?

Answer 5

What the drug does to the body

Question 6

What is pharmacokinetics ?

Answer 6

What the body does to the drug (metabolism)

Question 7

Define bioavailability?

Answer 7

The amount of administered drug reaching its target

Question 8

Define bioavailability?

Answer 8

The amount of administered drug reaching its target

Question 9

What is selectivity?

Answer 9

Drugs ability to preferentially produce a particular effect

Question 10

What influences selectivity ?

Answer 10

• chemical nature of the drug (how easily it crosses cell membranes
• specifity of interaction with molecular targets
• route of administration
• the dose
• patient differences

Question 11

What is carried out along with the specificity ?

Answer 11

Drug selectivity.
Very few drugs are specific enough for a single effect, therefore must test for:
-side effects/toxicity
-risk/benefit analysis §