Intro to Pharm

Question 1

4 ways to name drugs

Answer 1

Chemical name
Generic name
Proprietary (Trade) name
Street name

Question 2

Pharmacodynamics

Answer 2

What the drugs do to the body

Studies the effects of drugs on body processes

Question 3

Pharmacokinetics

Answer 3

What the body does to drugs

Studies the movement of drugs in the body

Question 4

2 factors important for receptor binding

Answer 4

Affinity

Shape/specificity

Question 5

Agonists

Answer 5

Have receptor affinity and intrinsic activity
Bind and cause a response
Often exogenous derivatives of an endogenous agonist

Question 6

Antagonists

Answer 6

Have receptor affinity but lack intrinsic activity

Bind, cause no action

Question 7

2 ways naloxone works

Answer 7

Blocks binding of agonist

Displaces agonist since it has a higher affinity for the receptor

Question 8

ED50

Answer 8

Dose required to produce a therapeutic effect in 50% of the population

Question 9

TI is calculated by dividing…

Answer 9

Toxic dose 50/effective dose 50

Question 10

3 things to consider when determining which route of administration to use

Answer 10

1. Drug characteristics
2. Patient characteristics
3. Therapeutic objectives

Question 11

Enteral administration

Answer 11

Through the GI tract
Gives systemic effects
Includes oral, sublingual and rectal

Question 12

Parenteral administration

Answer 12

Does not involve the GI tract

Usually injections

Question 13

5 routes of drug administration

Answer 13

Enteral
Parenteral
Inhalational
Topical
Transdermal