Intro to Path Flashcards
What is the definition of Pathology?
The scientific study of disease.
Disease is any alteration from a normal healthy state - whether or not changes ae clinically apparent.
What is a clinical pathologist interested in?
fluid chemistry, hematology, cytology.
will often recomment histopathology as the logical step forward.
What is an anatomic pathologist looking at?
Biopsy - tissue samples.
Necropsy (small percentage of overall case load).
Will often discuss findings with clinical pathologists.
H&E stain: what are the components of the stain? What component stains the nucleus? Cytoplasm/proteins? What color are these structures after the stain?
Hematoxylin and Eosin. Hematoxylin stains the nucleus blue, while Eosin stains proteins/cytoplasm red/pink.
What is the definition of pathogenesis?
The sequence of events in lesion development.
What is the definition of etiology? What are the different classifications of etiology?
The underlying cause.
i.e. bacteria, parasite, virus, etc.
Extrinsic - physical trauma, infectious organisms, toxins.
Intrinsic - spontaneous genetic mutations
Extrinsic + Intrinsic - nutrional abnormalities, workload imbalances, immunological dysfunction.
What is the definition of etiopathogenesis?
Combines the underlying cause and sequence of events in pathogenesis.
What is the definition of Diagnosis?
A concise statement or conclusion concerning the nature, cause or name of a disease.
Name the different types of diagnoses and give a brief definition.
Clinical diagnosis: using case hx, clinical signs, physical exam
Differential diagnosis: “rule outs”. list of diseases that could account for the lesions.
Clinical Pathological Diagnosis: concerned with changes in fluid chemistry, hematology, cytology.
Morphological diagnosis: after predominant lesions/structural changes. i.e. granulomatous enteritis
Etiological Diagnosis: after the specific causal agent. _ i.e. mycobacterium avium ssp. paratubercculosis enteritis_
What is a prognosis?
A statment of likely outcome of a condition. Requires a thorough understanding of pathogenesis.
good/excellent - complete resolution
uncertain/guarded - lesion might resolve or get worse
poor/grave - animal not expected to recover
