Intro to Oncology Flashcards

1
Q

What is cancer?

A

Abnormal growth and cell division
No apoptosis
Growth occurs at expense of other cells

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2
Q

What are the types of tumors?

A

Solid tumor (breast, prostate)
Liquid tumor (leukemia, lymphoma)

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3
Q

What are possible causes of cancer?

A

Genetics
Environmental
Occupational
Lifestyle
Viruses
Hormonal exposure (endogenous)
Drugs (anabolic steroids, chemo)

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4
Q

What are the types of tumors based on location?

A

Localized
Metastatic (colon cancer spreads to liver, then brain but still colon cancer)

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5
Q

When is cancer most curable?

A

before it metastasizes

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6
Q

What are the 3 treatment options for cancer?

A

Surgery
Radiation
Pharmacotherapy

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7
Q

When is surgery possible?

A

solid tumor

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8
Q

When is radiation possible?

A

superficial tumor

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9
Q

What are the 4 types of pharmacotherapy?

A

Chemotherapy
Targeted therapy
Biologic therapy (using the body to treat)
Hormonal Therapy

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10
Q

What is the standard of chemotherapy care?

A

combination chemotherapy with different mechanisms and non-overlapping toxicity

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11
Q

What does chemo destroy besides tumor cells?

A

Rapidly dividing cells:
Blood cells
Hair cells
GI cells
Reproductive tissues

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12
Q

What is adjuvant chemo?

A

chemo in addition to surgery to eliminate micrometastases

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13
Q

What is neoadjuvant chemo?

A

chemo before surgery to shrink the tumor prior to procedure

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14
Q

What is salvage chemo?

A

any chemo after initial failed attempt

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15
Q

What is curative intent?

A

prevent reoccurrence; maintain maximum doses and strict schedules due to high chance of cure

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16
Q

What is palliative intent?

A

prevent progression; dose reductions for toxicity and schedule changes reasonable

17
Q

What are tumor-specific factors?

A

Tumor type
Stage of disease
Genetics
Drug resistance

18
Q

What are patient-specific factors?

A

Performance status
Organ function
Body habits
Co-morbid conditions
Patient wishes