Intro To Neoplasia Part 1

Question 1

Malignant tumor of connective tissue, mesenchymal cells, or other non-epithelial cells. Tend to metastasize hematogenously.

Answer 1

Sarcoma

Question 2

Malignant tumor of epithelium (esp of skin) and lining of organs. Likely spread through lymphatics.

Answer 2

Carcinomas

Question 3

Germ cell tumor. Usually involves mature or immature ectoderm, endoderm, and mesoderm

Answer 3

Teratoma

Think teratogen - deveoplment - ectoderm/mesoderm/endoderm development

Question 4

Disorganized overgrowth of tissue in their native site

Answer 4

Hamartoma

Question 5

Normal tissue in a foreign location

Answer 5

Choristoma

Chorey is normally here

Question 6

Word meaning lack of differentiation

Technically means, “To form backward”

Answer 6

Anaplasia

Question 7

Word meaning variation in size and shape of cells

Answer 7

Pleomorphism

Question 8

Pre-malignant disordered growth. Cells may be Pleomorphic (higher N/C ratio). Cells have loss of uniformity of individual cells and loss of architectural orientation

Answer 8

Dysplasia

DISorder = DYSplasia

Question 9

Dysplasia involving entire thickness of epithelium but does NOT go through basement membrane

Answer 9

Carcinoma in situ

Question 10

Dysplastic epithelial cells that involve whole thickness of epithelium & breach basement membrane

Answer 10

Invasive carcinoma

Question 11

Grading of cancer based on:

Detemrined by:

Answer 11

Cellular appearance & mitotic activity

DEtemrined by microscopy

Question 12

Stage of cancer based on:

Determined by:

Answer 12

Localization/spread based on size, local and regional lymph node spread, and distant metastases

Determined by surgery and/or radiology