Intro to immunology Flashcards

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1
Q

what are the primary organs of immune system

A

thymus and bone marrow

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2
Q

what are the secondary organs of immune system

A

spleen, tonsil, lymph vessel, adenoids, skin, and liver

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3
Q

what are leukocytes

A

white blood cells that defend against foreign material

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4
Q

what are the 5 types of leukocytes

A

phagocytes, mast cells, eosinophils, basophils and natural killer cells

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5
Q

what is the most abundant phagocyte

A

neutrophils

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6
Q

the two types of lymphocytes of adaptive response

A

B cells and T cells

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7
Q

where do B cell mature

A

in the bone marrow

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8
Q

where do T cells mature

A

in thymus

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9
Q

what cells are seen in humoral response

A

B lymphocytes

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10
Q

what cells are seen in cell mediated response

A

T lymphocytes

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11
Q

what is an antigen

A

protein that binds to specific antibody

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12
Q

what is an antibody

A

protein made by B lymphocyte that binds to antigen

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13
Q

B cells have ___________ on surface

A

membrane bound antibodies

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14
Q

how does B cell become activated

A

when pathogen binds to antibodies

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15
Q

what do B memory cells do

A

will proliferate in response to pathogen

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16
Q

what do effector B cells do

A

they produce antibodies

17
Q

what is opsonization

A

when pathogen is tagged so phagocytes can eliminate

18
Q

what happens if pathogen attaches to antibody on B cell

A

B cell will engulf and break pathogen and attach it to MCH II and present antigen

19
Q

what is function of effector T helper cells

A

raises alarm and releases cytokines

20
Q

what are cytokines

A

chemical alarm for cells

21
Q

function of MHC I complex

A

bind to shady things inside of cells and present to membrane

22
Q

function of effector cytotoxic T cells

A

will bind to things that present same antigen on MHC I complex

23
Q

what occurs when effector Tc cells bind to MHC I complex

A

will release perforins or grazymes

24
Q

what does perforins do

A

causes gaps/holes on membrane

25
Q

granzymes do what

A

cause cells to kill itself