Intro to immunology Flashcards
what are the primary organs of immune system
thymus and bone marrow
what are the secondary organs of immune system
spleen, tonsil, lymph vessel, adenoids, skin, and liver
what are leukocytes
white blood cells that defend against foreign material
what are the 5 types of leukocytes
phagocytes, mast cells, eosinophils, basophils and natural killer cells
what is the most abundant phagocyte
neutrophils
the two types of lymphocytes of adaptive response
B cells and T cells
where do B cell mature
in the bone marrow
where do T cells mature
in thymus
what cells are seen in humoral response
B lymphocytes
what cells are seen in cell mediated response
T lymphocytes
what is an antigen
protein that binds to specific antibody
what is an antibody
protein made by B lymphocyte that binds to antigen
B cells have ___________ on surface
membrane bound antibodies
how does B cell become activated
when pathogen binds to antibodies
what do B memory cells do
will proliferate in response to pathogen
what do effector B cells do
they produce antibodies
what is opsonization
when pathogen is tagged so phagocytes can eliminate
what happens if pathogen attaches to antibody on B cell
B cell will engulf and break pathogen and attach it to MCH II and present antigen
what is function of effector T helper cells
raises alarm and releases cytokines
what are cytokines
chemical alarm for cells
function of MHC I complex
bind to shady things inside of cells and present to membrane
function of effector cytotoxic T cells
will bind to things that present same antigen on MHC I complex
what occurs when effector Tc cells bind to MHC I complex
will release perforins or grazymes
what does perforins do
causes gaps/holes on membrane
granzymes do what
cause cells to kill itself
