FINAL review

Question 1

antigens are

Answer 1

foreign substances to the body

Question 2

Antigen processing involves the breakdown of protein antigens and the subsequent association of peptide fragments on the surface of antigen presenting cells with

Answer 2

MHC class 1 or class 2 molecules

Question 3

clonal deletion of developing T lymphocytes takes place in which location of the body

Answer 3

thymus

Question 4

in adults, B cell maturation takes place in the

Answer 4

bone marrow

Question 5

normal response to infection is polyclonal production of antibodies

Answer 5

True

Question 6

one of the advantages of adaptive immunity over innate immunity is

Answer 6

the response is targeted against a single pathogen

Question 7

the antibody immune response is attributed to the action of

Answer 7

B lymphocytes

Question 8

The Fc portion of the antibody is formed by

Answer 8

lower portions of the heavy chains

Question 9

When a B cell encounters its corresponding antigen, it expresses more ____ in order to be more effective antigen presenting cell

Answer 9

MHC class 2

Question 10

when B cell reacts directly against an antigen, independent of T helper cells, does it produce antibody

Answer 10

yes, IgM

Question 11

Which cells have receptors for Fc portion of IgE

Answer 11

Mast cells

Question 12

Which of the following are characteristics of a plasma cell?

Answer 12

it secretes identical antibodies all directed at a single unique epitope

Question 13

Which of the following corresponds to the antigen binding site of immunoglobulins?

Answer 13

VH:VL

Question 14

Which of the following statements regarding CD8 T cells is incorrect?

Answer 14

when activated, CD8 T cells in turn activate B cells

Question 15

___ act as cellular messengers by delivering degraded pathogens to lymphoid organs:

Answer 15

dendritic cells

Question 16

___ form dimers; whereas ___ form pentamers

Answer 16

IgA; IgM

Question 17

the isotope of an antibody is determined by

Answer 17

constant region of heavy chain

Question 18

The process of __ results in change in the constant region of the heavy-chain of antibodies, causing a change in the effector function and transport properties of antibodies

Answer 18

isotype switching

Question 19

With the exception of B cells, all other cells of the body have the immunoglobulin genes in the

Answer 19

germline configuration

Question 20

Which of the following is incorrectly matched?

Answer 20

helper T cells; CD8

Question 21

After an initial exposure to a pathogen, the phenomenon of __ produces a faster, more effective response to subsequent exposures

Answer 21

immunological memory