intro to immunity and overview of epithelial surfaces Flashcards
what are examples of anatomic barriers to pathogens?
skin
oral mucosa
respiratory epithelia
intestine
what are examples of complement/ antimicrobial proteins?
C3
defensins
Reg III gamma
what are examples of innate immune cells?
macrophages
granulocytes
natural killer cells
what are examples of adaptive immunity cells?
B cells / antibodies
T cells
what are the 3 phases of the immune respone?
- innate immune response
- adaptive immune response
- immunological memory
what does the innate immune response phase involve?
inflammation
complement activation
phagocytosis and destruction of pathogens
how long after infection does it take for the innate response phase to occur?
minutes
how long does the innate immune response phase last?
for days
how long after infection does it take for the adaptive immune response to occur?
hours or days
how long does the adaptive immune response last?
days to weeks
how long after infection does it take for immunological memory to occur?
days to weeks
how long does immunological memory last?
can be lifelong
what chemical defences does skin epithelia posses?
fatty acids
beta defensins
lamellar bodies
cathelicidin
what chemical defences does gut epithelia posses?
alpha defensins
cathelicidin