intro to immunity and overview of epithelial surfaces Flashcards

1
Q

what are examples of anatomic barriers to pathogens?

A

skin
oral mucosa
respiratory epithelia
intestine

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2
Q

what are examples of complement/ antimicrobial proteins?

A

C3
defensins
Reg III gamma

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3
Q

what are examples of innate immune cells?

A

macrophages
granulocytes
natural killer cells

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4
Q

what are examples of adaptive immunity cells?

A

B cells / antibodies

T cells

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5
Q

what are the 3 phases of the immune respone?

A
  1. innate immune response
  2. adaptive immune response
  3. immunological memory
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6
Q

what does the innate immune response phase involve?

A

inflammation
complement activation
phagocytosis and destruction of pathogens

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7
Q

how long after infection does it take for the innate response phase to occur?

A

minutes

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8
Q

how long does the innate immune response phase last?

A

for days

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9
Q

how long after infection does it take for the adaptive immune response to occur?

A

hours or days

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10
Q

how long does the adaptive immune response last?

A

days to weeks

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11
Q

how long after infection does it take for immunological memory to occur?

A

days to weeks

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12
Q

how long does immunological memory last?

A

can be lifelong

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13
Q

what chemical defences does skin epithelia posses?

A

fatty acids
beta defensins
lamellar bodies
cathelicidin

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14
Q

what chemical defences does gut epithelia posses?

A

alpha defensins

cathelicidin

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