Intro To Histological Interpretation

Question 1

What 4 questions are asked to interpret a specimen

Answer 1

1. Is it normal?
2. If not, is it Inflammatory or Neoplastic
3. If neoplastic, is it Benign or Malignant
4. If malignant, is it Primary or Secondary

Question 2

Compare Primary and Secondary Malignancy

Answer 2

Primary: Originating from that tissue
Secondary: Spread from a primary tumour elsewhere

Question 3

Compare Benign and Malignant

1. Localised or spread?
2. Slow or rapid growth?
3. Good or poor differentiation?
4. Tissue compressed or Invaded, Destroyed?

Answer 3

Benign:

1. Localised
2. Slow growth
3. Well-differentiated
4. Compressed tissue

Malignant:

1. Spread
2. Rapid growth
3. Poorly-differentiated
4. Tissue invaded and destroyed