Intro to Hematology Flashcards
What is the normal pH range of blood?
7.35 - 7.45
What is the average temperature of blood?
100.4F
What is the average volume of blood in a healthy adult male?
5 - 6 Liters
What is the average volume of blood in a healthy adult female?
4 - 5 Liters
What percentage of the blood is made of Plasma?
55%
What percentage of the blood is made of Cells?
45%
Antibodies that transport proteins as well as fats, metal ions, and fat-soluble vitamins.
Globulins
Protein produced in the liver that helps form blood clots.
Fibrinogen
Protein that maintains oncotic pressure and acts as a transport protein for fatty acids, calcium, lipid soluble hormones, and even some medications.
Albumin
Where are Hematopoietic Stem Cells located?
Red Bone Marrow
Flexible and oval shaped cell that lacks a nucleus and most other organelles.
Erythrocyte
Oxygen bearing molecule found in erythrocytes.
Hemoglobin
What is the lifespan of mature Red Blood Cells?
100 - 120 days
What nutrients are required for Erythropoiesis?
Iron
Folic Acid
Vitamin B12
How is iron stored inside the body?
Ferritin
Converted to bilirubin, transported to the Liver, secreted into the intestine, metabolized to Stercobilin and then pooped out.
Heme
Metabolized into individual amino acids and released into circulation for reuse.
Globin
Low blood-oxygen causes what two organs to release Erythropoietin?
Kidneys
Liver
What is the main site for destruction of old and abnormal blood cells?
Spleen
Type of anemia where red blood cells are smaller than normal.
Microcytic
Type of anemia where red blood cells are normal in size, but there aren’t enough of them.
Normocytic
Type of anemia where red blood cells are abnormally large and don’t function properly, there are also fewer Red Blood Cells than normal.
Macrocytic
Percentage of red blood volume that is red blood cells.
Hematocrit
An abnormal increase in the number of platelets.
Thrombocytosis
An abnormal decrease in the number of platelets.
Thrombocytopenia
Name three granulocytes.
Neutrophils
Basophils
Eosinophils
Name two agranulocytes
Lymphocytes
Monocytes
Blood product that is usually only used with massive blood loss. Contains red blood cells, plasma, and fresh platelets.
Fresh Whole Blood
Blood product that is most commonly used to raise hemoglobin.
Packed Red Blood Cells
Why are most blood products leukocyte-poor?
Reduces complications
Blood that you donate yourself to be administered to yourself in anticipation of blood loss during a procedure.
Autologous Packed Red Blood Cells
Blood product that contains all the coagulation factors. Used to correct deficiencies or prevent coagulopathy in trauma patients receiving massive transfusions of Packed Red Blood Cells
Fresh Frozen Plasma
Blood product that is made from fresh plasma by cooling it and collecting the precipitate. Contains fibrinogen, Factor VIII, and von Willebrand Factor
Cryoprecipitate
