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Clinical Lab > Intro to Hematology > Flashcards

Intro to Hematology Flashcards

0
Q

Erythropoietin

A

Cytokine that influences stem cells to develop into red blood cells

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1
Q

Cytokines

A

Proteins involved in cell-to-cell communication and control stem cell differentiation into specific cell types

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2
Q

Blasts

A

Blood cells that are an immature stage of development

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3
Q

Where are blasts found?

A

Bone marrow

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4
Q

Three types of granulocytes

A

Granulocytes, monocytes, lymphocytes

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5
Q

Three types of granulocytes

A

Neutrophils, basophils, eosinophils

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6
Q

Innate immune response; what does it include?

A

How granulocytes respond to foreign cells; inborn, non-specific response that does NOT arise from previous infection and has NO memory; includes complement cascade with proteins that acts in sequence

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7
Q

Adaptive Immune Response

A

Acquired immunity; how lymphocytes respond to foreign bodies; involves method of learning and remembering antigens

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8
Q

What do monocytes play a role in?

A

Innate and acquired immunity

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9
Q

Anemia

A

Low RBC or low hemoglobin and hematocrit

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10
Q

What is anemia caused by?

A

Decrease in production, increase in destruction, or blood loss

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11
Q

Reticulocyte count

A

Lab value that measures immature RBC and is used to determine bone marrow activity

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12
Q

Mean corpuscular volume

A

Lab value that reflects the average size of RBCs; derived from a ratio or packed RBCs to total RBCs

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13
Q

Normocytic

A

RBCs are of average size; normal MCV

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14
Q

Microcytic

A

Small RBCs; low MCV

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15
Q

Macrocytic

A

Large RBCs; high MCV

16
Q

Normochromic

A

RBC having the normal color due to adequate hemoglobin; normal MCHC

17
Q

Mean corpuscular hemoglobin concentration

A

Lab value that estimates the hemoglobin concentration

18
Q

Is MCV or MCHC more helpful?

A

MCV

19
Q

Ferritin level

A

Determines available iron stores in the body

20
Q

Hemoglobin

A

Protein-iron compound in RBCs that carries oxygen and carbon dioxide

21
Q

What type of hemoglobin do infants have? Adults?

A

Infants- F; Adults- A1

22
Q

Hemoglobinopathy

A

Group of inherited disorders characterized by structural variations of the hemoglobin molecule

23
Q

Type of hemoglobin seen in sickle cell patients

A

Type Hb S

24
Q

Hemoglobin Electrophoresis

A

Lab test that identifies hemoglobin type

25
Q

Sickle cell anemia

A

Hemoglobinopathy that occurs in people homozygous for Hb S resulting in distorted and fragile RBCs

26
Q

Aplastic anemia

A

Anemia due to decreased RBC production; seen with pancytopenia and results from failure of bone marrow to generate new cells

27
Q

Hemolysis

A

Breakdown or destruction of RBCs

Clinical Lab (2 decks)

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