Intro to General Dermatology Flashcards
Give the basic arrangement of skin structure
Sub cutis
Dermis
Epidermis
What is the function of melanocytes?
Makes melanosomes which are excreted and phagocytose into keranocytes where they sit above the nucleus
What is the function of Langerhans cells?
Process antigens and migrate to lymph nodes to induce an immune response
What are the 5 layers of the epidermis? (inner to outer)
- Stratum basale
- Statum spinosum
- Stratum granulosum
- Stratum lucidum
- Stratum corneum
What does the sub cutis-hypodermis consist of?
Fat
What does the dermis consist of?
Collagen and elastin matrix with mucopolysaccharide gel
What cells are found in the dermis?
Fibroblasts
Dermal dendritic cells
Macrophages
How does the epidermis receive its nutrients?
By diffusion NOT blood vessels
Name some components of nail anatomy
Hyponychium Nail plate Lateral nailfold Nail bed Lunula Cuticle Proximal nailfold Proximal nailfold Nail matrix
What are the 3 stages of the hair cycle?
ANAGEN
CATAGEN
TELOGEN
Describe anagen
Active growing phase; 80-90% of hair
Describe catagen
2-3 week phase precedes telogen; growth stops/follicle shrinks; 1-3% of hairs
Describe telogen
Resting phase for 1-4 months; up to 10% of hairs in a normal scalp
What is the condition which involves temporary hair loss following shock, stress or a traumatic event?
Telogen effluvium
Give the 6 important functions of the skin (important exam question)
- Thermoregulation
- Skin immune system
- Barrier
- Sensation
- Vit D synthesis
- Interpersonal communication
What does the barrier function of the skin protect against?
Mechanical, chemical, microorganisms, UV light
What does the barrier function of the skin keep in?
Water + electrolytes, macromolecules
What aspects of interpersonal communication does the skin aid in?
Physical appearance
Smell
Self-identity
How does the skin aid in vit D synthesis?
UV light converts 7-dehydrocholesterol to cholecalciferol
Give the external causes of skin disease
Temp UV Chemical (allergen or irritant) Infection Trauma