Intro to Endocrine Flashcards
what does the Hypothalamus release?
TRH, CRH, GnRH, GHRH, Somatostatin, Dopamine
what does the Anterior Pituitary release?
TSH (thyroid stimulating hormone), FSH, LH, ACTH, MSH, Growth Hormone, Prolactin
what does the Posterior Pituitary release?
Oxytocin, ADH
what does the Thyroid release?
T3, T4, Calcitonin
what does the Parathyroid release?
PTH
what does the Pancreas release?
insulin, glucagon
what does the adrenal medulla release?
norepinephrine, epinephrine
what does the Kidney release?
renin, 1,25 dihydroxycholecalciferol
what does the Adrenal Cortex release?
cortisol, aldosterone, adrenal androgens
what do the Testes release?
Testosterone
Ovaries
Etradiol, progesterone
Corpus luteum
etradiol, progesterone
Placenta
hcg, estriol, progesterone, HPL
ACTH
adrenocorticotropic hormone
adh
antidiuretic hormone
crh
coticotropin-releasing hormone
dhea
dehydroepiandrosterone
dit
diiodotyrosine
doc
11-deoxycorticosterone
fsh
follicle-stimulating hormone
ghrh
growth hormone releasing hormone
GnRH
gonadotropin-releasing hormone
HCG
human chorionic gonadotropin
HGH
human growth hormone
HPL
human placental lactogen
IGF
insulin-like growth factor
LH
luteinizing hormone
MIT
monoiodotyrosine
MSH
melanocyte-stimulating hormone
PIF
prolactin-inhibiting factor
POMC
pro-opiomelanocortin
PTH
parathyroid hormone
PTU
propylthiouracil
SRIF
somatotropin release-inhibiting factor
T3
triiodothyronine
T4
thyroxine
TBG
thyroxine-binding globulin
TRH
thyrotropin-releasing hormone
TSH
thyroid-stimulating hormone
Hormone structures/ synthesis
- Peptide and protein hormones
- Steroid hormones (derivatives of cholesterol)
- adrenal and sex hormones
- Amine hormones (derivatives of tyrosine)
e. g. catecholamines and thyroid hormones
Endocrine Axis
Hypothalamus (releasing hormone)–> adenohypophysis (endocrine cell types in pars distalis–> tropic hormone) –> Peripheral endocrine gland (adrenal, thyroid, gonads, liver) –> peripheral hormone –> physiological responses
Measurement of hormone levels
Plasma analysis, urine analysis
Plasma analysis
Reflective only of time of sampling
Pulsatile secretion, diurnal variation, cyclic variation, age, sleep entrainment, hormone antagonism, hormone and metabolite interaction, and protein binding can all cause variation in hormone levels
Urine analysis
Restricted to the measurement of catecholamines and steroid hormones
Can reflect an integrated sample