Intro to Cardiovascular Disease Flashcards
What is hypertension?
Persistently high blood pressure >140/90mmHg
What drugs are taken by patients with hypertension and what do they do?
Aspirin - anti-platelet drug
Captopril - ACE inhibitor
Atenolol - b1-blocker
Candesartan - angiotensin II receptor blocker
Nifedipine - calcium ion channel blocker
Bendroflumethiazide - diuretic
What are the possible primary causes of hypertension?
Genetic
Environmental - obesity, alcoholism, salt intake, stress
What are the possible secondary causes of hypertension?
Renal disease
Pregnancy
Endocrine disease
Drugs
Coarctation of aorta
How is hypertension diagnosed?
3 occasions over a 3 month period (consistently) at least
How are the primary causes of hypertension treated?
(General advice)
Weight loss
Increased exercise
Reduce alcohol intake
Stop smoking
Reduce salt intake
What are the complications of hypertension?
Heart failure
Stroke (cerebrovascular accident/CVA)
Coronary artery disease/myocardial infarction
Renal failure
Peripheral vascular disease
What is considered severe hypertension?
> 180/110mmHg
How is hypertension relevant in dentistry?
Minimise stress and pain to prevent further increase in blood pressure
No problem with adrenaline in local anaesthetic (as long as no intravascular injection)
Controlled hypertension = treat as normal
Uncontrolled hypertension = delay treatment and refer to a GP
Severe hypertension = refer urgently to hospital
More likely to have post-operative bleeding
Likely to be taking aspirin
What are the oral manifestations of drugs used to treat hypertension?
ACE inhibitors = loss of taste, angioedema, lichenoid reactions
b-blockers = lichenoid reactions
Calcium ion channel blockers = gingival overgrowth
Diuretics = xerostomia
K+ channel activators = oral ulceration
What is xerostomia?
Dry mouth
What does haemostasis require?
Vasoconstriction
Platelet plug
Coagulation
What additional measures can be taken to achieve haemostasis?
Extra pressure
Minimise trauma
Sutures
Haemostatic material in sockets
Post-operative instructions
What drug is used to treat hypercholesterolaemia?
Simvastatin
What are the risk factors of deep vein thrombosis?
Immobility
Surgery
Obesity
Pregnancy
OCP
Smoking
What is the international normalised ratio?
How long it takes for blood to form a clot (therefore determines effect of an oral anticoagulant)