Intro to cancer and RT Flashcards
Common cancer in males in Australia
lung, bowel and prostate
Common cancer in females in Australia
breast, bowel and lung cancer
What is Carcinoma
Cancer derived from the lining cells of an organ
4 types of epithelium
Glandular (prostate, colon and breast
Squamous (oesophagus, skin)
Transitional (kidney, bladder, ureter, urethra)
Pseudostratified (trachea)
Sarcoma
o Cancer derived from the soft tissues of the body
Fat, muscle, nerves and CT
Includes bone and cartilage
Lymphoma
o Cancer derived from the WBC that are present in the lymphoid tissues in the body, nodes and spleen
o May arise from any organ and body side
Melanoma
o Cancer derived from melanocytes
Mole in a benign growth of melanocytes
Mole may turn malignant to become melanoma
Spread of cancer
- Primary Cancer
o Cancer in situ – localised
o Invasive – invades surrounding tissues - Secondary Cancer / Metastasis
o Cells move away from original primary invade other organs and bones
Routes of cancer spread
- Vascular (via the blood stream)
- Lymphatic (e.g., breast to axillary nodes)
- Body cavities (e.g., lung into the pleura)
- Natural passages (renal cancer to bladder via ureter)
- Inoculation/surgical contamination
Cancer treatments
- Surgery
- Chemotherapy
- Radiation Therapy
- Hormone Therapy
- Immunotherapy, targeted therapies
Delivery method - radiotherapy
- Superficial o Short distance, external o Energies (10kV – 150kV) o Peak Energy (10 – 1150keV) - Orthovoltage o Energies (100 - 500kV) o Peak Energy (100 – 500 keV) - Linear Accelerator o High energy x-rays ‘long’ distance o Photons (6MV to 21MV) - Brachytherapy o Uses a radiation source o ‘Short’ distance, internal
Site Specific Side Effects of Radiation Therapy
- Head and Neck (mucositis, xerostomia, oesophagitis)
- Abdomen (vomiting, diarrhoea)
- Brain (headaches, oedema, alopecia)
- Breast (skin reaction, possible lymphoedema)
Purpose of Planning in Radiation Therapy
- Decide how to direct radiation to the tumour
- Ensure normal tissue don’t receive too much dose
- Ensure critical structures are safe
Palliative Radiation Therapy
- Aims to improve quality of life by relieving symptoms without causing unacceptable side effects
- Good for patients with metastatic disease or large primary tumours where cure is not possible
- Involves delivering lower doses, often to larger volumes of tissue
Roles of Radiation Therapist
- Simulates the patient prior to the planning CT scan
- Creates the computer plan for the patient
- Deliver RT
- Ensure safety and accuracy
- Provide support and care