intro

Question 1

Describe unique characteristics of intracellular bacteria.

Answer 1

shielded from antibodies;
disease mechanism cannot be separated from host immune response;
tissue damage is caused by host response inflammation;

Question 2

what is the disease mechanism for tuberculosis and leprosy?

Answer 2

Macrophage activation resulting in granulomatous inflammation and tissue damage

Question 3

what is the disease mechanism for Legionnaires’ disease?

Answer 3

cytotoxin lyses cells and causes lung injury and inflammation

Question 4

Describe unique characteristics of extracellular bacteria.

Answer 4

disease is caused by 2 mechanisms;

inflammation and bacterial toxins

Question 5

What are toxins that bacteria have?

Answer 5

endotoxins: components of bacterial cell walls
exotoxins: secreted by bacteria

Question 6

What are some human diseases involving extracellular bacteria?

Answer 6

tetanus, meningitis, UTI, skin infections, food poisoning, etc.

Question 7

What are primary lymphoid organs?

Answer 7

bone marrow, thymus;

where lymphocytes are generated

Question 8

What are secondary lymphoid organs?

Answer 8

spleen, lymph nodes, mucosal immune tissue;

where lymphocytes are stored for fast response

Question 9

What does each immune cell do? named? lineage, etc

Answer 9

bach