Intro Flashcards

1
Q

Founder of modern pharmacology, known for his work on the correlation between chemicals and their effectiveness.

A

Oswald Schmiedeberg (1838-1921)

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2
Q

Developed aspirin (acetylsalicylic acid) in 1899.

A

Felix Hoffmann

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3
Q

Introduced cocaine as a local anesthetic.

A

Carl Koller

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4
Q

Developed the smallpox vaccine, leading to its global eradication by 1980.

A

Edward Jenner (1796)

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5
Q

Discovered vitamin D deficiency as the cause of rickets.

A

Edward Mellanby (1921)

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6
Q

Discovered insulin.

A

Frederick Banting & Charles Best (1921)

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7
Q

Discovered penicillin, a major breakthrough in antibiotics.

A

Alexander Fleming (1928)

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8
Q

Discovered streptomycin, used to treat tuberculosis.

A

Selman Waksman (1943)

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9
Q

Developed the first polio vaccine.

A

Jonas Salk (1955)

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10
Q

Developed the first polio vaccine.

A

Jonas Salk (1955)

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11
Q

Increased funding for the rehabilitation of drug addiction and tightened regulations on drug prescriptions.

A

Anti-Drug Abuse Acts of 1986:

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12
Q

Creation of the Philippine Drug Enforcement Agency (PDEA) to combat illegal drug activities.

A

EO 218

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13
Q

This amendment mandates that the Philippine Drug Enforcement Agency (PDEA) must have custody of all seized dangerous drugs to ensure proper handling and prevent misuse.

A

RA 10640 – Strengthening of Sec. 21 of RA 9165:

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14
Q

Philippine law aimed at safeguarding the country from the harmful effects of dangerous drugs. It provides strict regulations on drug use, distribution, and penalties for violations.

A

RA 9165 – Comprehensive Dangerous Drugs Act of 2002

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15
Q

Promotes the use of generic drug names in prescriptions

A

RA 6675 – Generics Act of 1988

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16
Q

This law aims to provide affordable and quality medicines by regulating the prices of essential drugs.

A

RA 9502 – Cheaper Medicine Act of 2008

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17
Q

The first national drug law in the United States, requiring accurate labeling of medicines to ensure public safety.

A

Pure Food and Drug Act of 1906

18
Q

Forbade the sale of substantial doses of opiates or cocaine except by licensed doctors or pharmacies

A

Harrison Narcotic Act of 1914

19
Q

A label required on tobacco products in the United States, warning about the health risks associated with smoking and tobacco use

A

Surgeon General’s Warning

20
Q

A US federal law that established schedules for classifying controlled substances, regulating their manufacture, distribution, and use

A

Comprehensive Drug Abuse Prevention and Control Act of 1970

21
Q

Study of substances that interact with living systems through chemical processes.

A

Pharmacology

22
Q

Use of alcohol in nutrition, medicine, and rituals.

A

Stone Age Medicine

23
Q

First use of inorganic salts as medications.

A

Hippocrates

24
Q

Promoted a dogmatic approach to medicine.

A

Galen

25
Q

Introduced the concept of dose-response and stated, “The dose makes the poison.”

A

Paracelsus

26
Q

Movement of a drug into the bloodstream after administration.

A

Absorption

27
Q

Movement of a drug to and from blood and tissues.

A

Distribution

28
Q

Drug that activates receptors to produce a desired response.

A

Agonist

29
Q

Drug that prevents receptor activation, blocking a response.

A

Antagonist

30
Q

Ratio between the effective dose and lethal dose.

A

Therapeutic Index

31
Q

Range between the minimum effective concentration and minimum toxic concentration

A

Therapeutic Window

32
Q

Always undesirable and can lead to toxicity.

A

Adverse Effects

33
Q

Unrelated physiological effects of a drug, can be desirable or undesirable.

A

Side Effects

34
Q

Initial higher dose of a drug at the start of treatment.

A

Loading Dose

35
Q

Time it takes for half the drug to be eliminated from the body.

A

Half-Life

36
Q

Beneficial effects not due to the active properties of the treatment, but the patient’s belief.

A

Placebo Effect

37
Q

Failure to achieve the desired therapeutic effect, caused by factors like poor compliance or drug interactions.

A

Therapeutic Failure

38
Q

Study of how drugs are formulated and delivered to achieve their therapeutic effect.

A

Pharmaceutics

39
Q

Breakdown of a drug into smaller particles.

A

Disintegration

40
Q

Process of drug particles dissolving in the GI tract.

A

Dissolution

41
Q

Drugs that affect multiple receptor sites.

A

Non-Specific Drug Effects

42
Q

Drugs that affect multiple types of receptors.

A

Non-Selective Drug Effects