Intro Flashcards
years lost to disability
- mental illness has the most
- greatest burden for ages 9-49
- combined percent in adulthood more than all other causes combined
- several muscuoskeletal disorders are nervous system
why more questions?
- complexity
- hundreds of cell types
- each cell interacts with dozens-thousands of others
- constantly changing nature of interactions
- produces wide range and diversity of behavioral responses or deficits
philospohers
-Galneus, da Vinci, Vesalius
three questions
- what is a nervous system
- why do we have one
- is ours unique
- anemone vs sun dews
why we evolved
- make our lives more meaningful-beneficial to individual organism, species, or ecosystem
- selection of most meaningful/adaptive behaviors
- we create multiple representations of the outside world to steer internal decisions
three absic functions
- receive information-sensation
- create internal maps of information-perception
- respond in an adaptive manner to stimuli-action
nervous system
- internal and external sensory to cerebral hemispheres, diencephalon, cerebellum, brainstem, spinal cord
- then out to visceral or somatic motor system to effectors
distinguishing features of advanced nervous system
- cellular specializations
- areal specializations (collections of cells grouped together for common purpose)
- functional cooperation (ensembles of neurons acting in synchrony to produce desired outcome
- adaptability
- high information storage capacity
cellular specializations
- at least 200 different types of neurons
- cajal and golgi
- cortical pyramidal cells
- retinal bipolar
- retinal ganglion cell
- retinal amacrine cell
- cerebellar purkinje cells
varieties of neuroglia cells
- astrocyte
- oligodendrocyte
- microglial celll
- glial stem cell
- oligodendrocyte precursor
- myelinating oligodendrocyte
astrocytes
- a glial cell in CNS
- star like
- long cytoplasmic processes which bridge neurons and cap endo cells
- mechanical and metabolic support
- regulate environment
- contribute to blood brain barrier and control transport of substances
- coordinate nerve pathway development
- from embryonic ectoderm
oligodendrocyte
- a glial cell in CNS
- limited number of dendritic processes
- electrical insulation for a few adjacent neurons and forms part of the myelin sheath for their axons
- from embryonic ectoderm
microglia
- glial cell in CNS named for its characteristic small size
- derived from hematopoetic sources and provide a protective function to nervous tissue
- can become phagocytic
dendritic spines
- endings of dendrites where synapse occurs
- peak 8-12 years
areal specializations
- collections of cells grouped together for a common purpose
- arabic numbering system of all the brain tissue
- neocortex-motor and visual
- paleocortex
- archicortex
- lobes, fissures
functional cooperation
- ensembles of neurons acting in synchrony to produce a desired outcome
- froggy legs
- galvani’s method
sensory/afferent neurons
- typically have long dendrite and short axon
- carry messages from sensory receptors to the CNS
- free with little or no myelin-most sensitive to pain and temp
- thicker arise from pacinian and meissner- light touch and vibrations
- ruffini and merkel sustained pressure
motor/efferent neurons
-long axon and short dendrites and transmit messages from the CNS to the muscles or glands
interneurons
-found only in CNS where they interconnect neurons
lower level
-spinal cord ensembles
upper levels
cortical ensembles
simple reflex
- knee jerk
- hammer tap stretches tendon which stretches sensory receptors in leg extensor muscles
- sensory neurons synapses with motor neuron and interneuron
- interneuron inhibits flexor and motor neuron excites extensor muscle
- leg extends
homunculus diagram
- representative of sensory receptors in body
- face lateral down to feet medial then genitals
adaptibility
- functional stretch reflex
- calf muscles activate and you tilt but then our body shuts off the reflex and you don’t tilt as much and your calf stops firing
high information storage capacity
- we are wired to process information even if you are not aware of it
- sensory input, association, evaluation and planning, commands for movement, motor output