Intravenous Anaesthetics Flashcards
Name two common side effects of propofol
Hypotension and apnoea
Is propofol associated with prolonged sedation?
Nope, it is associated with rapid induction and awakening
Why is continuous infusion of propofol preferred over multiple doses when it is used for maintenance?
Multiple doses lead to consumption of more drug
Continuous infusion has short context half time
Is malignant Hyperthermia a contraindication of propofol?
Nope, it is even preferred to be used in patient at a high risk of malignant hyperthermia
Name a feared side effect of ketamine
Emergence delirium and bad dreams
Note: Desflurane also causes this
Does sodium pentothal(thiopental) lead to prolonged sedation?
Yes, it is a barbiturate
What is the commonest use of thiopental in anaesthesia?
For neurosurgery
Note: Isoflurane is also used for neurosurgery
In addition to neurosurgery, what are the OTHER uses of thiopental in anesthesia. 2
Used intraoperatively for burst suppression and for treatment of raised intracranial pressure.
Does thiopental protect the brain from ischemia?
Yes, it reduces brain oxygen consumption
Name a drug abuse that is closely associated with ketamine.
LSD
Which IV induction agents have fewer hemodynamic effects?
Etomidate
List three possible side effects of etomidate
Adrenal suppression
Myoclonus
Activation of seizure foci
Does Ketamine cause increased respiratory secretions?
Yes, that is why sometimes pretreatment antisialagogue such as glycopyrrolate is given
State a contraindication of ketamine
History of coronary artery disease and intracranial pathology
Should lidocaine be given before injection of propofol?why or why not?
Yes, propofol injections are painful and also lead to a burning sensation
Note: Another thing to limit the pain is by using a large vein
State 3 uses of propofol
Maintenance anaesthetic
For Low dose sedation during regional ANAESTHESIA and monitoring anaesthesia
Used for patients in the ICU
