Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

GI Pharmacology > Intestinal motility, secretion, nausea and vomiting > Flashcards

Intestinal motility, secretion, nausea and vomiting Flashcards

1
Q

what type of mechanism is vomiting

A

defence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is the main site for sensing emetic stimuli

A

Chemoreceptor trigger zone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

which cells sense toxic chemicals/toxins in the gut

A

Enterochromaffin cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

examples of antihistamines

A

cyclizine, promethazine, diphenhydramine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

which receptors are antihistamines antagonists for

A

H1 receptors in the brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

when are antihistamines indicated

A

naseau and vomiting - motion sickness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

side effects of antihistamines

A

sedation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

example of antimuscarinic

A

scopolamine (Hyoscine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what are antimuscarnics indicated for

A

motion sickness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

side effects of antimuscarincs

A

dry mouth
tachycardia
constipation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

examples of 5-HT3 receptor antagonists

A

ondansetron
granisetron
palonosetron

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

where do 5-HT3 receptor antagonists act

A

CTZ of medulla in hindbrain

GI tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

side effects of 5-HT3 receptor antagonists

A

constipation, diarrhoea, headache

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

examples of dopamine receptor antagonists

A 
chlorpromazine
droperidol
haloperidol
prochlorperazine
metoclopyramide 
domperidone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

where do D2 receptor antagonists act

A

CTZ of medulla in hindbrain

GI tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

which dopamine receptor antagonists doesn’t act at the CTZ

A

domperidone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

examples of Neurokinin-1 receptor antagonists

A

fosaprepitant

aprepitant

18
Q

where do NK1 receptor antagonists act

19
Q

what do NK1 receptor antagonists block the effect of

A

substance P

20
Q

side effects of NK1 receptor antagonists

A

constipation

headache

21
Q

examples of anti-diarrhoeal drugs

A

loperamide

diphenoxylate

22
Q

side effects of anti-diarrhoeal drugs

A

constipation
sedation
respiratory depression

23
Q

what is the bulk forming laxative

A

ispaghula husk

24
Q

what is the osmotic laxative called

25
Q

what is the stimulant purgative laxative that increases electrolyte and water secretion from renal mucosa

26
Q

cyclizine

A

antihistamine

27
Q

promethazine

A

antihistamine

28
Q

diphenhydramine

A

antihistamine

29
Q

scopolamine

A

antimuscarinic

30
Q

ondansetron

A

5-HT3 receptor antagonist

31
Q

granisetron

A

5-HT3 receptor antagonist

32
Q

palonosetron

A

5-HT3 receptor antagonist

33
Q

chlorpromazine

A

dopamine receptor antagonist

34
Q

droperidol

A

dopamine receptor antagonist

35
Q

haloperidol

A

dopamine receptor antagonist

36
Q

prochlorperazine

A

dopamine receptor antagonist

37
Q

metoclopramide

A

dopamine receptor antagonist

38
Q

domperidone

A

dopamine receptor antagonist

39
Q

fosaprepitant

A

NK1 receptor antagonist

40
Q

aprepitant

A

NK1 receptor antagonist

41
Q

loperamide

A

anti-diarrhoeal drug

42
Q

diphenoxylate

A

anti-diarrhoeal drug

GI Pharmacology (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions