Intervertebral_Disc Flashcards
1
Q
Intervertebral disc collagen
Annulus
Nucleus
A
Intervertebral disc collagen
Annulus - Type I
Nucleus - Type II
2
Q
Aggrecan primary function in intervertebral disc
A
The primary function of aggrrecan, the most abundant proteoglycan in the intervertebral disc, is to maintain water content.
Early in life, aggrecan has a high chondroitin sulfate content which changes to more keratin sulfate and less water.
3
Q
HNP associated with spontaneous increase in interleukin-1 beta which increase production of
A
Matrix metallproteases, nitric oxide, interleukin-6, and prostaglandin E2
