intervertebral disc Flashcards
what is the cervical nucleus pulpous composed of?
fibrocartilage
what is the consequence of non-aggregated GAGs in the lumbar nucleus pulposus?
the nucleus pulposus will lose water under deformation conditions
what cell is associated with the nucleus pulposus until about age 11?
notochord cells
which type of collagen is dominant in the nucleus pulposus?
type II collagen
what is unusual about the cervical annulus fibrosus?
it lacks any lamellar or layered organization
what is the appearance of the cervical annulus fibrosus?
horse-shoe with the anterior margin thick and lateral margins tapering to the uncinate processes; posterior margin is thin
what is the organization of the lumbar annulus fibrosus?
it has 12-14 concentric cylindrical lamellae
what is the water concentration in the lumbar annulus fibrosus at birth and after 30?
birth- 78%
30- 70%
which is stronger, ALL or PLL?
ALL is stronger
what is the consequence of aggregated GAGs in the lumbar annulus fibrosus?
annulus fibrosus will retain water under deformation conditions
which type of collagen is dominant in annulus fibrosus?
type I collagen
what is the organizational pattern for collagen fibers in the annulus fibrosus?
they are parallel with one another in a single lamellus and angled
what is the organization of collagen fibers between lamellae?
collagen fibers will be angled in the opposite direction such that a spiral- counter spiral is observed
what is the average angle of collagen fibers within the annulus fibrosus?
they average about 50-60 degrees
what is the principle type of collagen fiber within the cartilage end plate?
type II collagen fiber
