Interoduction Of Physiology Till The AP L1-L5 Flashcards

1
Q

What is the physology ?

A

Is sinces of body function

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2
Q

Without physiology medcine will be ?

A

Quackery ( quackery mean dishonset practice )

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3
Q

why physiology is hard and interesting ?

A

It is difficult because master it you should know the basics o
chemistry, physics, biology, anatomy and histology.
And it is interesting because you will see for the first time in your lives how those separate sciences you have been studying for many years;

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4
Q

All chemicals are compsed of ?

A

Particales

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5
Q

The structure of all substance is the same and incloulds ?

A

Atom , a molecule , a nucleus , electron , proton , neutron , ion

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6
Q

What is the atom ?

A

Its the smallest chemical partical of a substance , it consist of posativly chargeed neuclues and negativly charged electrons

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7
Q

Atomic nucleus is formed of ?

A

Proton which have postive charge , and neutrons which have no charge

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8
Q

The charge of magnitude of an atomic nuecleus ?

A

Is equal to the number of protons in an atom

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9
Q

The atom is electrically neutral

A

Yes

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10
Q

The number of the electoron in the atom equal ?

A

The number of proton in its nucleus

Ex: an oxgyn atom has 8 proton thus the charge magnitud of its atom its neucleus plus 8

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11
Q

What is the atom charge ?

A

Atom has no charge

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12
Q

what is the molecule ?

A

it is an electrically natural set for atom that form a definite structure using chimerical bond ex: water molecule

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13
Q

explain the charged particles

A

charged particles called ions can arise from electrically neutral atoms or molecule

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14
Q

explain how the positive charged ions form

A

its form if an atom or molecule if it loses one electron or more
and its called anions
EX; if potassium loses one electron its becomes K+

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15
Q

explain how negative charged ions form

A

its form if atom or molecule attached to electron and its called Cations
ex if florin attaches to electron its becomes F-

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16
Q

the proton is in the atomic nucleus is always ?

A

H + hydrogen plus = ionized hydrogen

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17
Q

explain the OH-group and H-group

A
  • oh group[ always carry negative charge

- H -group is always carry positive charge

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18
Q

explain the idea of opposite charges

A

opposite charges attract each other therefore , ions with deferent
charges from a molecule
ex: suodium + and chlorein - = ketchin salt
ex2: soduim + and hydrocarbonate - = baking soda

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19
Q

explain the Acid :

A

Acid is sour bcs it has excess of protons
ex : hydrocloric acid one of the strongest acid and its part of the gastric Juies
H+ and Cl- = HCL

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20
Q

acidity of the medium is expressed by symbol ?

A

PH

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21
Q

what is the pH

A
PH its indicates the number of the protons 
the high  PH its less acidity 
Ex: Gastic jueis =1.5-2.0 Ph 
slaiva = 7.0
blood = 7.37-7.47
pancreatic juies = 8.0
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22
Q

what is the most acidty in the body and the smallest ?

A

most is the gastric jueis = 1.5 - 2.00

smallest = pancreatic jiues = 8.0

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23
Q

when we consider the solution is acid

A

if its less 6.0

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24
Q

when we consider the solution is Basic

A

its its above the 6.0

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25
Q

acid and basics ?

A

are solutions nut they are antagonists

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26
Q

ac1d1ty of a solution affects not only of protons contents , but also the contents of any other substances which these pro o
may bind into atoms ( yes or no )

A

yes

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27
Q

anions. Roughly speaking, any an1on

attracts H+ ( yes or no )

A

yes

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28
Q

hydrogen does not have acidic properties

true or false

A

true

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29
Q

The ability to bind H is called ? and the substance that make it called ?

A

basic property
and substances that make it are
called “bases”

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30
Q

how dose the acidosis happened ?

A

That is hydrogen acidifies the medium (reduces

pH)

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31
Q

how dose the alkalosis happened ?

A

when the bases reduce acidity (pH increases)

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32
Q

what is The most basic properties

A

hydroxyl ions - OH-. When interacting with protons they give

water

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33
Q

explain alkaline action of hydroxyl anions ?

A

The alkaline action of hydroxyl anions is so strong tha an
01 gan1sm has specific mechanisms that facilitate conversation
of OH into HCQ3-. Hydrocarbonate ions bind protons loose
(but also possess basic properties):

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34
Q

what is the main source of the hydrocarbon anions in a body ?

A

molecules of sodium bicarbonate (baking soda NaHCO
and of
potassium bicarbonate (KHC0
3).

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35
Q

explain the «love» to exchange between acid and base

A

Acid and base «love» to exchange their ions.
ex : If in a
jar with water we add acid and salt (and bases ref r
to salts), then they will be constantly exchanging
their ions , substances will constantly pass into each other.

the same thing happened in the blood though such as solution called basic buffer

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36
Q

what is the basic buffer ?

A

its weak acid and salt

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37
Q

write the formula of the basic buffer

A

> > > >

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38
Q

what is the important properties ( function ) of the buffer

A
  • maintaining blood Ph at the same level even if acid or base are added

ex : adding hydrochloric acid to our formula
hydrochloric acid creates an excess of protons , trying to overacidty of the medium
however excess of the protons combined with the hydrocarbonate anions
contained in the buffer and carbonic acid is formed which dissociate immediately
to water and carbon dioxide that’s is the excess of protons passed into the water by the buffer , and in the water hydrogen has not acid properties

Ex : when we eat a lot of lemon or Vinegar pH of
our blood will not change. In addition 1t
important to note that blood buffer is in close connection with kidneys and lungs actions. Kidneys and lungs also regulate blood pH in holistic organism.

kidneys excrete water , lungs - carbon dioxide all this shifts buffer balance to
decrease the number of the protons , therefore intensive breathing or urine formation develops an alkalosis

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39
Q

what is the buffer capacity ?

A

is The number of basic ions in the buffer

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40
Q

All substances are divided into ?

A
  • organic substances : These
    substances are called organic because all the cells and tissues of a
    body consist of them. , also are those which have carbon in its structure (with
    the exception of carbides, oxides of carbon and cyanides)
  • mineral (inorganic) ; All other substances are called inorganic, since
    they existed from the very beginning of the universe, long before life
    appeared
41
Q

what is the electrical current and how it formed ?

A

electrical current : is one way movement of electrically charged particles in electric field

formed : if electrically charged particles of the body fall into an electric field they may get the ability to move all together in the same direction This creates
an electric current.

42
Q

what is the Electric field properties:

A
  • it always exists around a charged particle;
  • invisibility;
  • electric fields interact only with electric fields
  • vector. that is it has a direction
  • it can attract or repel electric particles
  • its has the property concentration and
    heterogeneity
43
Q

explain the electoral field concept ?

A

the closer two charges , are the greater there electrical fields overlap
the stronger there are attracted to each other (if there charges were opposite ) or repelled from each other ( if there charges were similar )

44
Q

what is the law explain the motion of the particles in the electrical field ?

A
its ohm's law 
I = U/R 
I = current intensity
U= potential difference
R= resistance
45
Q

what is the current intensity

A
  • current intensity : is muserd in amperes (A) its charactrasied the amount of charges passing though the conductor cross section per unite of the time
    the more charges move by the conductor the greater the intensity of electrical currant
    by simple way we could say
    the current intensity is the electrical current
46
Q

what is the nesscery condition for ohms law to work

A

its two
R= reactance
U = potential defiance

47
Q

what is the conductor

A

is any substance that is able to conduct electricity
meaning it has free charges: electrons or protons or ions. The more
free charges the matter has, the better it
conducts current.
ex: water and metal a good conductors
–Metals conduct electricity well, there are a lot of free electrons, which
are constantly jumping from one atom to another.
–water a molecule of water is electracally neutral , the water molecule is dipole in one side it has H+ and the other side oH-

48
Q

what is the dielectric ?

A

its any substance unable to conduct electricity
meaning it has no free charges , all particles sit on neutral atoms and molecule
ex / rubber or wood

49
Q

explain why the dry air is good conductor of electricity

A

bcs it has a great resistance and that explain the dielectric properties

50
Q

is the cells , tissue , organs , skin a good conductors ?

A

they consist of 60% water and skin is the good conductor especially
dry skin bcs its has a great resistance and that’s expressed the dielectric properties

51
Q

what is the potential difference ?

A

is the difference of charges in electrical field .
any 2 charges create a potential difference between them ,
but if the have low magnitudes and situate at great distance from each other
the potential difference between them is negligible

another explanation / is can be giving by Voltage
voltage is the strength of an electric filed the higher its voltage is the greater is current intensity is the greater resistance of the conductor

52
Q

what is the voltage

A

is the strength of an electric filed

and is another explanation of the potential difference

53
Q

what conidiation are necessary to create an electric current ?

A

1- availability of the conductor

2 - presence of potential difference

54
Q

can there be a conductor without an eclectic current ?

A

no , there is no electrical filled inside a conductor so no electrical current can flow through it

55
Q

can there be a conductor without an eclectic current ?

A

no , there is no electrical filled inside a conductor so no electrical current can flow through it

56
Q

can be there an electrical current without potential difference ?-

A

no
whiteout a potential difference electrical current cant flow bcs we know that’s an electrical current flows between two points due to the potential difference between them , thus as long as the potential difference there , the electrical current keep continue

57
Q

can be there be potential difference without an electrical current >?

A

yes , can be voltage without a elcictracl current for instance if you have a singl charge that charge induces a voltage in space even if its empty voltage is most physical way is a scalar filed

58
Q

can be there an electrical current whiteout a conductor ?

A

there is no electrical filed inside a conductor so no electrical current can flow though it

59
Q

what is the normal physiology ?

A

its the since about heathy body function

60
Q

what is the physiology ?

A

its the study about body function regulation

61
Q

what is the regulation mean ?

A

its mean the mechanism or increasing or decreasing i the actively of tissue , organs , or organ system in order to achieve a certain result

62
Q

what’s the physiologist interested in ?

A

they are interested in
1- mechanism of body function regulation
ex / how the muscles are contract or how gastric juies is secrets , or ow urin formation happened
2- with what a propose of regulatory process take place
ex/ what for stimulations of cardiac activity happens in stressful situation
and what about breathing decreasing at rest time

63
Q

what is the function of the hemostats miniating

A

its to hold the internal environment in the holistic organism

64
Q

explain the concept of homeostasis

A

the concept of hemostasis or to be more precisely
dynamic homeostasis its relative dynamic constancy of the internal environment
and of some physiological function of humane body and animals
ex for these function / blood circulation , metabolism thermoregulation .

65
Q

what is the homeostasis parameters

A

its individual process each of which can be charectrazid by its own
ex / blood PH , calcium concentration in interstitial fluid or blood
glycose level

66
Q

what is the homeostasis ?

A

is set of response that ensure maintaining constancy of the internal environment of the body , in condition of ever changing states of external environment

ex for homeostasis /
even if the body in cold the temperature should remine 36.6 C

67
Q

what is the homeostatic constants may flucatet

A

that’s is change their value in different condition at different kind of influence
, by the impact of external environment

ex / you ate a lot of sugar , glycose concentration in the blood increased
,ex2 / you start running the respiratory rate increased

68
Q

what is the homeostatic indices ?

A

its the make of rigid and non-rigid

69
Q

what is the rigid ?

A

its Constance capable of changing their value within small limits
ex / blood PH 7.35 -7.43

70
Q

what is the non-rigid ?

A

its Constance capable of changing their value about half or even serval times
Ex / glycose in the blood 3.3 -6.6

71
Q

mechanism of maintaining homeostasis ( types )

A

its two type

  • 1- humoral regulation
  • 2- nervous regulation
72
Q

what is the humoral regulation ?

A

is regulation by secretion of substance into the body fluid mediums ( blood , lymph, interstitial fluid

ex /adrenalin though the blood stimulate heart activity

73
Q

what is the nervous regulation ?

A

its carried out though central nervous system which implements the reflexes

ex of reflexes / arm withdrawal upon finger prick
head turning towered upon light

74
Q

what is the function of excitable tissue ?

A

is the basic concept of physiology

75
Q

how the two main mechanism of homeostasis being implemented ?

the meachanims is nervous and humoral

A

they are implemented through of so-called excitable tissue

76
Q

the exitance of the excitable tissue was first described by >?

A

glavani and mattucce

77
Q

classification of tissue by physiologist

A

1- excitable tissue

2- irritated tissue

78
Q

DF of irritability

A

is the ability to respond to irritation ( or exaction sensation )

under irritability physiologist understand the ability of cell , tissue , organ to respond somehow to irritation

79
Q

DF of excitability

A

is the ability to react to irritation ( or exaction )

excitability is meant a highly specific kind of irritability associated with the ability of cell or tissue to generate action potential (AP)

80
Q

irritability is non-specific notion

ex for this

A

you hit the subcutaneous fat then the hematoma can form bruise in the area of hematoma in all cell metabolic reaction somehow change

81
Q

irritability is non-specific notion

ex for this

A

you hit the subcutaneous fat then the hematoma can form bruise in the area of hematoma in all cell metabolic reaction somehow change

82
Q

all cell body are ( irritable or excitable ) ?

and why

A

irritable

bcs its can change their metabolism

83
Q

what are the tissue in the body can generate AP ?

A

1 glandular
2 macular
3 nervous

84
Q

what glandular tissue mean in histology and physiology ?

A
  • –in histological point its mean the epithelial cells all epithelial cells are belong to irritable tissue
  • – in physiological point its mean secretory cells , secretory cells ( glandulocytes ) are not only irritable but also excitable bcs they generate AP
85
Q

what is the rest potential RP ? and how its formed ?

A

its membrane potential of excitable tissue in a condition of rest

its formed when sodium channel closed and potassium open and cl- open
in the absence of action , potassium and sodium pump’s function , its pumps out the sodium from the cell and pumps the potassium into the cell , for every 3 ions of the sodium pumps the 2 ions of potassium are pumped as result the concentration of the potassium in the cell 30 time greater then extracellular environment

86
Q

what is the gradient ?

A

gradient from Latin is walking or growing

its vector indicating the direction of some parameter increasing

87
Q

types of gradient and the type of there passive transport

A

1 - concantration _____ diffusion
2- electrasic _______ diffusion
3- hydrostic ______ filtration
4- osmosis _____ osmotic

88
Q

DF of pumps and function

A
Pump's  conduct ions actively with  energy consumption of
  adenosine triphosphate(ATP) 
pumps pass ions actively  from a solution where is few of them into solution where a lot of them
89
Q

how dose resting potential arise ?

A

all cells both irritable and excitable have a membrane difference of optional
( electrical charges) this property is common between irritable and excitable tissue called RP

90
Q

how action potinal arise ?

A

AP occur when the membrane potinale is of specific cells location rapidly rises and falls , this is depolarization then courses adjacent location to similar depolarization and occur in serval types of animal cells called excitable cells which incloud , neurons cells , macular cells , endocrine cells

91
Q

explain the AP (all of it)

A

1- all the cell irritable and excitable have membrane potential similar to RP
in irritable tissue under normal condition membrane potential doesn’t change in any cases , but excitable tissues under some condition they change their potential .

2- changes in RP leading to AP generation , one of the main condition of AP generation is action of irritant in holistic organism irritant is work from outside the cell , irritation from an external is the triggering moment of generation of AP

3- under the action of exterior irritant the condition of channels and pump’s changes depolarizations start by opened of sodium +channel sodium ( and potassium pumps and sodium pumps is closed )start to enter the cell bringing positive charges with it , then RP membrane changes to opposite this is the first phase , and depolarization is passive process bcs pumps are closed
when depolarization takes a place cells perfumes its specific function
muscles contracts , glandular cells secrets their secretory products , neurons generates and conduct impulses .

4- then what happened for example in depolarization the muscles contract its should be return to rest and that’s what its called Repolarization .
in repolarization phase the pump’s K+ and Na+ are open , and its pump’s the sodium out fast which entered the cell in the depolarization , and they intensively pump’s the potassium in for potassium in the cell is not to much all K+ channels are open through them a lot of potassium goes back to outer surface
and the 3rd phase take place which is hyperpolarization

5- if excess positive charge outside the cell formed that’s mean negative charge in side the cell formed , this exsseceviness called hyperpolarization
then the cell returned to RP

92
Q

why membrane potinale called that way ?

what (De) , ( hyper ) , ( Re ) mean ?

A
its name that's derived from Latin polarization its mean ( electric charge ) 
the prefix  ( De )  its mean absents , cancelation , elimination  
the prefix  ( Re) its mean renewal repolarization mean , its renewal the charge to rest 
 the prefix  ( hyper )  its mean excess of  hyperpolarization mean  , excess of charge
93
Q

what is RP ?

A

its membrane charge at rest

94
Q

what is AP ?

A

its membrane potential in response to irritation

95
Q

what is the the parts ( or phases ) of AP

A

1 - Depolarization
2- repolarization
3 - hyperpolarization

96
Q

what is the depolarization in short way ?

A

its positive charge entering the cell

97
Q

what is the repolarization in short way ?

A

its retraining of the membrane potential to resting potential

98
Q

what is the hyperpolarization in short way ?

A

acclamation of excess positive charge on the outer surface of a membrane potinale due the K+