Internal Outpatient Flashcards
deHTN treatment if diabetes? stroke? CAD? CHF? pregnant?
diabetes, stroke –> ACEI
CAD, CHF –> BB
preg –> CCB
side effects of niacin and fibrates?
niacin: flushing, hyperglycemia, hyperuricemia (check CK, LFTs)
fibrates: hepatoxicity, rhabdo, cholesterol gallstones (check CK, LFTs)
de quervian disease
pain at radial wrist with thumb gripping
Dx: finkerstein test (clench thumb under other fingers then ulnar deviate wrist)
tx: thumb spica splint + NSAIDs
age related macular degeneration
degeneration of macula –> loss of central vision, scotoma (blind spot)
wet: sudden onset
dry: gradual onset
Dx: drusen (yellow-white deposits under pigmented epithelium)
Tx for wet: ranibizumab dec rate of vision loss
glaucoma
inc intraocular pressure –> optic nerve damage –> loss of peripheral vision, blindness
open angle: gradual onset, usually asx for years
closed angle: sudden onset w/ severe eye pain, tearing, N/V
Dx: check CNII damage, visual field defects, tonometry to measure IOP
Tx open angle: BB, alpha agonists, acetazolamide, prostaglandins
Tx closed angle: pilocarpine + emergent iridectomy
blepharitis
eyelid inflammation due to staph aureus
tx warm compress
complication of giant cell arteritis
aortic aneurysm
tx: follow patients with serial Xrays
treatment for torsades
if hemo unstable: defibrillator
if hemo stable and conscious: IV Mg
Common causes of aortic aneurysms
ascending: cystic medial necrosis (occurs w/ aging) or CT d/o
descending: atherosclerosis
clinical clues of renal parenchymal dz (3)
- HTN
- elev Cr
- abnorm urinalysis
indications for carotid endarterectomy
females: 70+ % stenosis
males sxs: 50+ stenosis
males asx: 60+ stenosis
acute aortic dissection tx
pain control (morphine)
IV BB (esmolol)
Na nitroprusside if SBP >120
surgery if ascending
complications of acute aortic dissection (8)
- stroke
- acute aortic regurg
- Horner syn
- acute MI
- pericardial effusion
- hemothorax
- LE weakness/ischemia
- abdominal pain
cholesterol crystal embolism
risk factors: HLD, HTN, DM II, cardiac Cath, vascular procedure
sxs: livedo reticular, ulcers, gangrene, blue toe syndrome); kidney injury; CNA prob; hollenhorst plaques on eye; GI issue
lab: elev Cr, elev Eos, low C’; urinalysis usually benign
skin/renal biopsy: biconvex, needle shaped clefts w/in occluded vessels, perivasc inflammatory w/ eos
indications for statin therapy
CV event
LDL>190
40-75 w/ DM
ASCVD risk >7.5%
presentation of constrictive pericarditis (8)
exertion dyspnea, fatigue periph edema and ascites inc JVP pericardial knock pulses paradoxus kussmauls sign pericardial thickening and calcification on imaging prominent X and Y descent
lights criteria for exudative effusion
only need 1
pleural fluid protein/serum protein ratio >0.5
pleural fluid LDH/serum LDH >0.6
pleural fluid LDH >2/3 upper limit of normal for serum LDH
Wells criteria for PE
> 4 PE likely
+3 if clinical signs of DVT, other dx less likely
+1.5 if previous PE/DVT, HR >100, recent surgery or immobilization
+1 if hemoptysis, cancer
renal calculi tx
inc fluid intake
dec Na intake
norm Ca intake
hyposthenuria
impaired ability of kidney to [ ] urine due to RBC sickling in the vasa rectae of the inner medulla
found in patients with sickle cell dz or trait
management of uncomplicated ureteral stones <1 cm
hydration
analgesics
alpha blockers
milk alkali syndrome
pathophys: excess intake of Ca and alkali; renal vasoconstriction and dec GFR; renal loss of Na and water, reabsorption of bicarb
sxs: NV, constipation; polyuria/dipsia; neuropsych sxs
lab: hyperCa, meta aka, AKI, suppressed PTH
tx: d/c cause agent; isotonic saline then furosemide
clinical ass'n FSGS membranous nephropathy MPGN minimal change IgA
FSGS: AA & hispanic, obesity, HIV, heroin
membranous nephropathy: adenoCA, NSAIDs, Hep B, SLE
MPGN: Hep C & B, lipodystrophy
min change: NSAIDs, lymphoma
IgA: URI
indications for cystoscopy (6)
- gross hematuria w/ no evidence of glomerular dz or infection
- microscopic hematuria w/ no evidence of glomerular dz or infection but inc risk of CA
- recurrent UTI
- obstructive sxs w/ suspicion for stricture, stone
- irritative sxs w/o UTI
- abnormal bladder imaging or urine cytology