Internal Organs Flashcards

1
Q

Oral Cavity

A
  • divided into vestibule and oral cavity proper
    • vestibule: part lying between lips and cheeks, and the teeth. In it the canal of the parotid gland is opened at the level of the upper 2nd molar tooth
    • oral cavity proper: bound by hard and soft palates superiorly, and the tongue and floor of the mouth inferiorly; the entrance of the oropharynx posteriorly. Ducts of submandibular and sublingual empty
  • lymphatic tissue which surrounds the oropharynx:
    • palatine tonsils
    • lingual tonsils
    • pharyngeal tonsils
    • tubal tonsils
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2
Q

Lip (labium)

A
  • core of striated muscle (m. orbicularis oris) embedded in fibroelastic CT
  • outer surface covered with skin- stratified squamous keratinised, containing many hair follicles and sebceous glands, and sweat glands
  • red transitional zone between outer skin and inner mucous membane
  • inner surface covered with mucous membrane and is stratified squamous nonkeratinised. Labial glands seen
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3
Q

Hard Palate

A
  • containing bone, bisected into right and left halves by raphe
  • anteriory the hard palate contins fatty tissue in the submucosa, posteriorly there are mucous glands
  • The maxillary nerve branch of the trigeminal nerve supplies sensory innervation to the palate.
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4
Q

Soft Palate

A
  • posterior border in the midline: uvula
  • two folds: palatoglossus and palatopharygeus; between them palatine tonsils
  • muscle fibres:
    • m. palatoglossus
    • m. palatopharyngeus
    • m. tensor veli palatini
    • m. levator veli palatini
    • m. uvulae
    • The tensor veli palatini is innervated by the medial pterygoid nerve, a branch of mandibular nerve, the third branch of the trigeminal nerve (CN V) - the only muscle of the palate not innervated by the vagus nerve.
  • the mucous membrane lining the oral surface is stratified squamous nonkerat. The pharyngeal surface is pseudostrat cilliated columnar
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5
Q

Tongue

A
  • mucous membrane of upper surface us divided into anterior two thirds (corpus linguae) and posterior pharyngeal part (radix linguae). Divided by sulcus teminalis; the apex of this sulcus projects back to a small pit (foramen cecum)
  • 4 types of papillae:
    • filliformes: most numerous and smallest, keratinised stratified without taste buds
    • fungiformes: on dorsal surface, mostly at the apex. Taste buds present in the covering strat squam nonkerat
    • vallatae: 10 to 12 in number, in a row immediately in front of sulcus terminalis. Surrounded by moat-like invagination lined with nonkerat strat squam that contains numerous tastebuds. Von Ebners glands (lingual salivary) emty their serous secetions andflush material from the moat.
    • folliatae: parallel low ridges separated by deep mucosal clefts, aligned at right angles to the longitudinal axis of the tongue. Occur on lateral edge of tongue. May not be recognised in aged humans. Taste buds
  • mucosa of the pharyngeal part of the dorsum contains many lymphoid follicles that form the lingual tonsils in the lamina propria
  • muscles: intrinsic and extrinsic
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6
Q

Salivary Glands

A
  • minor salivary glands:
    • labial, lingual, buccal, palatine
    • located in submucosa
    • empty directly into cavity via short ducts
  • major salivary glands:
    • paired parotid, sublingual and submandibular
    • surrounded by a capsule of moderately dense CT
  • acini of salivary glands contain either serous cells (protein secreting), mucous cells (mucin secreting) or mixed
  • serous acini:
    • spherical
    • nuclei centrally located
    • secretory zymogen granules
  • mucous acini:
    • tubular in shape
    • mucous cells are polyhedral in shape and surround a large lumen
    • flat nuclei, basally located
  • mixed acini:
    • cap of serous cells that secrete into a highly convoluted intercellular space lumen. called serous demilunes
  • lumen of salivary acinus:
    • continuous with that of a duct system, having 3 sequential segments; intercalated duct, striated, excretory. All with cuboidal epithelium
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7
Q

Glandula Parotis

A
  • largest pair of salivary glands
  • below external acoustic meatus, between mandible and sternocleidomastoid
  • duct opens oposite 2nd uper molar
  • surounded by fibrous capsule, septa divide into lobes and lobules
  • secretory portion is tubulo-alveolar serous acini
  • serous cells roughly cuboidal or pyramidal in shape
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8
Q

Glandula Sublingualis

A
  • below the floor of the mouth, anterior to submandibular glands
  • secretions enter by 8 to 20 short ducts
  • not surrounded by fibrous capsule
  • mucous and serous, mostly mucous acini
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9
Q

Glandula Submandibularis

A
  • below the floor of the mouth, beneath the body of the mandible
  • ducts open on either side of the frenulum of the tongue, just behind the lower incisor teeth
  • surrounded by fibrous capsule. Almost no adipose tissue within the gland
  • mucous and serous types, mostly serous
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10
Q

Histological Structure of Alimentary Canal

A
  1. tunica mucosa:
    1. lamina epithilialis: separates the lumen of the digestic tract from the body of the organism. Synthesises and secretes digestive enzymes, hormones, mucus, antibodies.
      1. in the oesohagus, stratified quamous nonkeratinised
      2. small intestine, simple columnar
      3. anal part of rectum: strat squam nonkera
    2. lamina propria: often rich in elastic fibres. provides nutrient vessels, glands, GALT, growth factors
    3. lamina muscularis mucosae: boundary between mucosa and submucosa. inner circular and outer longitudinal layer can b distinguished
    4. lamina submucosa: strongest layer, bundles of collagen. also contains the largest arterial network of the wall. submucosal plexus (of Meissner) is a network of symp and paasymp nerves
  2. tunica muscularis: distinct inner circular and outer longitudinal layers. Create waves of peristalsis. Myenteric (auerbachs) plexus lies between circular and long layers
  3. serosa and adventitia:
    1. the serosa is part of the visceral peritoneum that attaches the organs to the abdominal wall. consists of thin CT layer (lamina subserosa) covered by mesothelium (simple squamous)
    2. the portions of the digestive tract that do not possess a serosa are attached by a loose CT, the adventitia. Blends with general CT of adjoining structures
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11
Q

Pharynx

A
  • musculomembranous tube extending from the base of the skull to 6th cervical vertbrae, where it becomes continuous with the oesophagus
  • 3 parts:
    • nasopharynx
    • oropharynx
    • laryngopharynx
  • auditory eustachian tubes connect nasopharynx to each middle ear
    • pharyngeal tonsils at posterior wall of nasopharynx
    • tubal tonsils near opening of eustachain tubes
  • pharynx has a musculomembranius wall that is deficient anteriorly. Replaced by:
    • posterior nasal apertures
    • oropharyngeal isthmus
    • inlet of the larynx
  • wall has 3 layers:
    • mucous
    • fibrous
    • muscular
  • part of pharynx susceptible to abrasion: nonkeratinised stratified squamous (continuous with oral cavity and oesophagus)
  • respiratory portion has pseudostrst cilliated columnar
  • muscular layer consists of superior, middle and inferior constrictors, stylopharyngeus, palatopharyngeus, salpingopharyngeus (levator muscles, fibres run longitudianlly)
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12
Q

Oesophagus

A
  • 25cm long
  • pharynx to stomach
  • cervical, thoracic and abdominal part
  • anatomical constrictions:
    • at its commencement 15 cm from incisors
    • where crossed by left principle bronchus (27.5 cm)
    • as it transverses the diaphragm (40 cm)
  • 2 physiological constrictions:
    • where crossed by aortic arch (22.5 cm)
    • as it enters the stomach
  • wall consists of 3 layers:
    • mucous membrane
    • muscular coat
    • adventitia
  • lamina epithilialis starts off as strat squam nonkerat, then becomes simple columnar
  • lamina propria: oesophageal cardiac glands
  • tunica muscularis: upper third is straited muscles, in the middle the straited nd smooth muscle are interwoven; distal third is smooth muscle
  • tunica adventitia, until oesophagus enters abdominal cavity where it is covered by serosa
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13
Q

Stomach

A
  • 2 surfaces:
    • anterior and posterior, lesser and greater curvatures
  • 2 orifices: cardiac and pyloric
  • intraperitoneal
  • fundus: usually full of gas
  • body: extends from level of cardiac orifice to the level of incisura angularis
  • pyloric antrum: from incisura angularis to the proximal limit of the pylorus. Pylorus is the most tubular part; it’s thick muscular wall forms the pyloric sphincter
  • cavity of pylorus is called the pyloric canal
  • stomach lining thrown into longintudinal folds called rugae, prominent in the lower regions
  • at higher magnifications, numerous openings called foveolae (gastric pits), into the bottom of which open 3 to 7 tube shaped gastric glands
  • glands: cardiac, pyloric and fundic or gastric
  • each gland has neck, body and bottom
  • glands of the fundus and body:
    • chief or peptic: pepsinogn and a weak lipase
    • parietal or oxintic: produce HCl and intrinsic factor
    • mucous neck cells
    • argentaffin: enteroendocrine
    • undfferentiated: stem cells
  • cardiac glands: secrete mucous
  • pyloric glands located in pyloric antrum, enteroendocrine and occasional parietal cells
  • gastric tunica muscularis:
    • outer long
    • middle circular
    • inner oblique
    • auerbachs plexus innervates them
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14
Q

Small Intestine

A
  • extends from pylorus to ileocecal junction
  • duodenum: 25 cm
  • jejunum: 2.5 m
  • ileum: 3.5 m
  • principal site for digestion and absorption
  • simple columnar, absorption and reabsorption. Microvilli present
  • plicae circulares; permanent transverse folds. Becme reduced in size and number in the middle of the ileum
  • cells:
    • absorptive cells
    • goblet cells
    • argentaffin cells
    • paneth cells: evidence that they secrete lysozyme
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15
Q

Duodenum

A
  • superior part (intraperi), decending, horizontal, ascending (all retroperi)
  • submucosa contains Brunners glands; secrete watery fluid rich in bicarbonate, which hel neutralise the acid secretions of the stomach
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16
Q

Jejunum and Ileum

A
  • begins at duodenojejunal junction, ileum ends at ileocecal junction
  • coils of the small intestine are attached to the posterior abdominal wall by a fan-shaped fold of peritoneum known as the mesentary of the small intestine
  • intraperitoneal
17
Q

Large Intestine

A
  • 1.5 m long
  • function: absortion of fluids and solutes
  • 3 main parts:
    • cecum: lies in right iliac fossa
      • ileocecal orifice called ileocecal valve
      • cecum leads to veriform appendix and colon
    • colon (ascending, transverse, descending, sigmoid)
    • rectum
  • differences from small intestine:
    • intestinal villi absent
    • longitudinal layer forms 3 teniae colli
    • circular plicae changed into semilunar
    • colon wall has sacculations (haustrae coli)
    • small adipose projections: appendices epiploicae
  • epithelium consists of:
    • columnar cells
    • mucous cells
    • microfold cells
    • stem cells
    • enteroendocrine cells
    • brush cells
  • lamina propria: cryts of lieberkuhn
  • teniae coli: taenia libera, mesocolica, omentalis
  • covered by serosa
18
Q

Rectum

A
  • 12 cm long, same diameter as the signoid colon above. Lower part dilated as rectal ampulla
  • most distal: anal canal
  • anal glands secrete mucus
  • distal portion of the anal canal is lined with stratified squamous epithelium, continous with that of the perineal area
  • circular layer of tunica muscularis thickens to form internal anal sphincter
  • external anal sphincter formed by striated muscles of perineum
19
Q

Liver

A
  • lobes:
    • right lobe:
      • right
      • caudate
      • quadrate
    • left lobe
    • right and left lobe may be separated by:
      • fissure for ligamentum teres
      • fissure for ductus venosus
  • situated in right hypochondriac region, 1.5 kg, intraperitonesl apart from area nuda
  • functional blood supply from portal vein
  • nutritional blood supply from hepatic artery
  • covered by thin CT capsule of Glisson that becomes thicker at the hilum (porta hepatis)
  • porta hepatis: portal vein, hepatic artery, common bile duct (common heptaic duct from right and left, and cystic)
  • ligaments:
    • falciform: left triangular and coronary ligament which becomes right triangular lig (area nuda)
    • teres
    • venosum
    • lesser omentum
  • portal triads:
    • 6 triads per lobule
    • venule from portal vein
    • arteriole from hepatic artery
    • bile duct
    • lymphatic vessels
  • lobules:
    • central vein
    • hepatocytes
    • 6 triads
    • liver sinusoids
    • space of disse separating endothelial cells from underlying hepatocytes
    • Kupffer phagocytic cells
    • fat storing Ito cells in SoD
20
Q

Gall Bladder

A
  • neck, body and fundus
  • attached to lower surface of liver, communicates with hepatic duct through cystic duct
  • mucosa composed of simple columnar cells
  • no glasnds apart from perhaps mucous glands in the neck
  • thin muscle layer
  • contraction induced by CCK
21
Q

Pancreas

A
  • head, body and tail
  • mixed exocrine and endocrine gland, produces enzymes and hormones
  • exocrine: compund acinar, similar to parotid
  • pancreatic duct and bile duct go to ampulla hepatopancreatica which opens in descending part of duodenum
  • pancreas covered by thin capsule of CT that sends septa into it, separating pancreatic lobulesw
  • enzymes:
    • trypsinogen
    • chymotrypsinogen
    • carboxypeptidase
    • ribonuclease
    • deoxyribonuclease
    • elastase
    • amylase
22
Q

Respiratory System

A
  • organs divided into conducting portions and respiratory portion
  • conducting portion:
    • nose
    • pharynx
    • larynx
    • trachea
    • bronchi
  • respiratory portion:
    • respiratory bronchioles
    • alveolar ducts
    • alveolar sacs
    • alveoli
  • functions: air conduction, filtration and gas exchange
23
Q

Nose

A
  • external nose and nasal cavity
  • external nose:
    • free tip and root
    • 2 nistrils (nares)
    • bone and hyaline cartilage
  • nasal cavity:
    • from the nostrils in front to the choanae behind
    • nasal septum made of bone posteriorly, and hyaline cartilage anteriorly
  • lateral wall of nasal cavity marked by 3 projections: sup, mid and inf conchae
  • the area below each concha is called a meastus
  • chambers are divided into 3 regions:
    • vestibule
    • respiratory segment
    • olfactory segment
  • vestibule:
    • stratified squamous epith
    • stiff hairs, vibrissae
    • sebaceous glands
    • posterior vestibule: nonkerat strat squam, continues posteriorly with pseudostrat cilliated columnar
  • resiratory mucous membrane:
    • pseudo cilliated columnar cells have 5 types:
      • cilliated
      • goblet
      • brush
      • small granule
      • basal
    • olfactory epithelium:
      • olfactory cells- bipolar neurons
      • supporting
      • basal
      • brush
    • olfactory glands (Bowmans) deliver proteinacious secretions via ducts onto the olfactory surface
  • paranasal sinuses:
    • ethmoidal, frontal, maxillary, sphenoid
    • maxillary, frontal and ant ethmoid drain into middle meatus
    • post ethmoid and sphenoid empty into space above superior concha
    • lined with mucous membrane
24
Q

Larynx

A
  • muscles:
    • intrinsic:
      • cricothyroid
      • cricoarytenoid: posterior and lateral
      • arytenoid: transverse and oblique
      • thyroarytenoid
      • all innervated by recurrant laryngeal branch of vagus; apart from cricothyroid which is innervated by external laryngeal branch of superior laryngeal nerve
    • extrinsic:
      • sternothyroid
      • omohyoid
      • sternohyoid
      • inferior constrictor muscles
      • thyrohyoid
      • digastric
      • stylohyoid
      • myohyoid
      • geniohyoid
      • hyoglossus
      • genioglossus
  • irregularly shaped hyaline cartilages: paired and unpaired;
    • paired: aytenoid, coniculate and cuneiform
    • unpaired: cricoid, throid and epiglottis
  • lined by mucous membrane, on each side are the vocal ligaments; ligaments produce vocal folds. the gap between the vocal folds is called the rima glottidis
  • stratified squamous epith on oral side, and pseudostat cilliated columnar on respiratory side
25
Q

Laryngeal Cavity

A

The laryngeal cavity (cavity of the larynx) extends from the laryngeal entrance downwards to the lower border of the cricoid cartilage where it is continuous with that of the trachea.

It is divided into two parts by the projection of the vocal folds, between which is a narrow triangular fissure or chink, the rima glottidis.

The portion of the cavity of the larynx above the vocal folds is called the vestibule; it is wide and triangular in shape, its base or anterior wall presenting, however, about its center the backward projection of the tubercle of the epiglottis.

It contains the ventricular folds, and between these and the vocal folds are the ventricles of the larynx.

The portion below the vocal folds is called the infraglottic cavity. It is at first of an elliptical form, but lower down it widens out, assumes a circular form, and is continuous with the tube of the trachea.

26
Q

Trachea

A
  • 10 cm long, 2.5 com diameter
  • continuous with lower larynx, at hte level of the sternal angle, it divides into right and left primary bronchi
  • lumen stays open because of arrangement of c-shaped cartilage bars. located posteriorly, tracheal muscle
  • wall of trachea, 4 layers:
    • mucosa: ciliated pseudostrat columnar
    • submucosa: dender CT, seromucous glands
    • cartilaginous: hyalin cartilage. tunica fibro-musculo-cartilaginea
    • adventitia: CT
27
Q

Bronchi

A
  • trache divides into R and L main bronchi
  • right bronchus wider and shorter
  • bronchial tree:
    • primary bronchus
    • lobar (3R 2L)
    • segmental (11R 10L)
    • lobular bronchiole
    • terminal bronchiole (non cilliated simple columnar or cuboidal)
    • respiratory bronchiole
    • alveolar duct
    • atrium
    • alveolar sac
    • alveoli
  • bronchioles possess no cartilage
  • wall of bronchus can be regarded as having 5 layers:
    • mucosa
    • muscularis
    • submucosa
    • cartilage layer
    • adventitia
  • 8 types of epithelial cell:
    • cilliated
    • goblet
    • serous (IgA)
    • clara cells (secretes lipoprotein to prevent luminal adhesion)
    • undiferentiated basal cells
    • intermediate epithileocytes
    • brush cells
    • dense core granulated cells (Kultchitsky): neuroendocrine, similar to argentaffin cells
28
Q

Respiratory Portion

A
  • pulmonary acini are smaller units of structure that make up the lobules
  • each acinus consists of a terminal bronchiole and respiratory bronchiole, and alveoli
  • respiratory bronchioles: 1st part that allows gas exchange to occur. Cuboidal epithelium
  • alveoli:
    • alveolar epithelium:
      • type 1 cells
      • type 2 cells cuboidal, surfactant producing
      • alveolar phagocytes
  • respiratory memrane 0.5 micrometres
29
Q

Pleura

A

In human anatomy, a pleural cavity is the thin fluid-filled space between the two pleurae (visceral and parietal) of each lung. Left and right pleural cavities surround the left and right lungs respectively. A pleura is a serous membrane which folds back onto itself to form a two-layered membranous structure. The outer pleura (parietal pleura) is attached to the chest wall, but is separated from it by the endothoracic fascia. The inner pleura (visceral pleura) covers the lungs and adjoining structures, including blood vessels, bronchiand nerves.

The visceral pleura receives its blood supply from the bronchial circulation, which also supplies the lungs. The parietal pleura receives its blood supply from the intercostal arteries, which also supply the overlying body wall.

The costal and cervical portions and the periphery of the diaphragmatic portion of the parietal pleurae are innervated by the intercostal nerves. The mediastinal and central portions of the diaphragmatic pleurae are innervated by the phrenic nerves. The visceral pleurae covering the lung itself receive their innervation from the autonomic nervous system and have no sensory innervation. Only the parietal pleurae are sensitive to pain.

30
Q

Peritoneum

A
  • retropeitoneal:
    • kidneys
    • ureters
    • urinary bladder
    • uterus
    • desc, hori, asc duodenum
    • body and head of pancreas
  • mesoperitoneal:
    • ascending colon
    • descending colon
    • gall bladder
  • intraperitoneal:
    • stomach, the first 5 centimeters and the fourth part of theduodenum, jejunum, ileum, cecum, appendix, transverse colon, sigmoid colon, and the upper third of the rectum, as well as, the liver,spleen, and the tail of the pancreas.
31
Q

Urinary System

A
  • paired kidneys, ureters
  • urinary bladder, urethra
32
Q

Kidneys

A
  • produce urine, also function as an endocrine organ, producing erythropoeitin which regulates RBC formation; and renin which cleaces AT to produce AT 1
  • 12th thoracic to 3rd lumbar
  • upper pole has suprarenal glands