Internal Anatomy of the Brain Flashcards
1
Q
Formation of the caudate and hippocampus
A
- As the telencephalon expands anteriorly and inferiorly to form the temporal and frontal lobes, the neural tube folds with it to become the LVs
- The hippocampal formation and caudate nucleus follow the growth of the LVs into the temporal lobe, forming C-shaped structures
2
Q
Internal structure of the lateral ventricles
A
- The shape of the LVs will change depending on the plane of section
- In coronal sections, going anterior to posterior, the LVs starts as thick (in the anterior horn)
- Around where the anterior horn meets the body of the LVs, the LVs look very thin in a coronal section (you can also see the 3rd ventricle directly btwn and inferior to the LVs)
- In the body of the LV (in a coronal section) the inferior horn will be visible as a space btwn the medial temporal lobe and the rest of the brain. The third ventricle will also be seen in this plane
- In the atrium of the LV there is a large aggregate of choroid plexus, the glomus
3
Q
Corpus callosum
A
- The corpus callosum runs directly superior to both LVs in all coronal sections
- These white fiber tracks are commissural fibers (connect neurons on right side to those on left side)
- Those that interconnect the frontal lobes: genu
- Interconnect parietal lobes: trunk
- Interconnects occipital lobes and posterior temporal lobes: splenium
- The anterior commissure interconnects the the anterior temporal lobes (circumscribed bundle of axons in front of the column of the fornix)
4
Q
Basal ganglia 1
A
- Consist of caudate nucleus, putamen, and globus pallidus
- The caudate nucleus alone follows the C-shaped LVs
- The head of the caudate lies in the frontal lobes and sits laterally to each LV
- The head then becomes the lentiform nucleus (composed of the putamen more anterior-lateral, with the globus pallidus more posterior-medial). The globus pallidus does not extend as far anterior or posterior as the putamen
- Globus pallidus is composed of 2 parts: externa and interna. Both are medial to the putamen
- The internal capsule runs directly btwn and separates the caudate and the putamen/globus pallidus
5
Q
Basal ganglia 2
A
- Moving posteriorly from the head of the caudate, the body extends along the frontal lobes through the parietal lobes still forming the lateral walls of the LVs
- In the temporal lobe the tail of the caudate is the superior surface of the inferior horn of the LV
- The tail of the caudate finally abuts the amygdala in the temporal lobe
- The putamen and the globus pallidus (just lateral to the caudate, separated by the internal capsule) together make up the lentiform nucleus (regulation of motor functions)
6
Q
Hippocampal formation 1
A
- Part of the cerebral cortex is invaginated into the ventricle during development and forms the hippocampus in the temporal lobe
- This structure is the inferior wall of the inferior horn of the LV
- The hippocampus then curls back (posterior/superior) following the shape of the LV
- Extending from the hippocampus (still tracing the LV), and moving more medial as it curves superior/anterior, is the fornix
- The fornix begins at both hippocampus as crura and then meet under the splenium to form the body of the fornix, just superiorly to the thalamus
7
Q
Hippocampal formation 2
A
- Moving anteriorly, the body of the fornix then separates into two columns that turn inferiorly and descend posterior to the anterior commissure
- These extensions end in the mammillary bodies of the hypothalamus
- The fornix forms the medial wall of the LVs
- The hippocampus is part of the cerebral context and consolidates short-term memory (does not store long-term memory)
- Damage to hippocampus results in inability to form new memories (anterograde amnesia)
8
Q
White matter tracts of the cerebral cortex 1
A
- 3 different groups: association fibers, commissural fibers, or projection fibers
- Association fibers interconnect different cortical areas within the same hemisphere
- Short association fibers are U-shaped bundles of axons that connect adjacent gyri (gyrus-gyrus; as in the different areas of the sensory cortex)
9
Q
White matter tracts of the cerebral cortex 2
A
- Long association fibers interconnect lobes-lobes on the same hemisphere and allow for integration of motor, sensory and special sensory info
- One important long association tract is the arcuate fasciculus, which connects Broca’s area to Wernicke’s area and is essential for normal comprehension and expression of language
- The cingulum is a major association tract of the limbic system and lies deep to the cingulate cortex, it connects the frontal cortex and thalamus to the temporal lobe
10
Q
White matter tracts of the cerebral cortex 3
A
- Commisures connect the two hemispheres of the brain, this includes the parts of the coups callosum (genu, trunk, splenium) and the anterior commissure
- Projection fibers form the major afferent and efferent connections of the cortex and run bidirectionally btwn the cortex and subcortical structures (basal ganglia, thalamus, brainstem, spinal cord)
- The internal capsule is an example of projection fibers
11
Q
Internal capsule
A
- A dense collection of motor (efferent) and sensory (afferent) axons that brings together the collection myelinated fibers (corona radiate) from various lobes of the brain
- The different components (sensory vs motor) are contained in specific subdivisions of the internal capsule
- It is located btwn the caudate (lateral to the caudate) and the lentiform nucleus (medial to the putamen and glolbus pallidus)
- Medial to lateral: fornix->LV->caudate->internal capsule->lentiform nucleus (globus pallidus-> putamen)
12
Q
Hypothalamus
A
- Located below the anterior commissure and just lateral to the 3rd ventricle
- The anterior commissure separates the lentiform nucleus from the hypothalamus
- Optic tracts are just inferior-lateral to the hypothalamus
13
Q
Thalamus
A
- Forms the inferior/lateral border of the LV (just inferior to the caudate)
- Extends down to form the superior/lateral border of the 3rd ventricle
14
Q
Amygdala
A
- Located in the temporal lobe, large area that is bordered just medially by the uncus
- Therefore just deep to the uncus lies the amygdala
- The amygdala is smooth, and differs in appearance from the hippocampus (hippocampus is convoluted)
- Amygdala is more anterior than the hippocampus (more posterior)
15
Q
Insula
A
-Gyrus that is the lateral border of cortex btwn the frontal/parietal lobes and the temporal lobes