Interactions between viruses and humans Flashcards
are viruses living or non-living?
non-living
what is the structure of a virion?
- virus genome
- protein capsid (multiple coat proteins)
- may also have an envelope
what are retroviruses?
single stranded RNA viruses that convert their RNA into DNA
what are hepadnaviruses?
double stranded DNA viruses that convert DNA into RNA?
how does a viruses replicate?
- attachment
- entry
- replication
- assembly
- release (cell lysis/budding)
what are examples of viruses transmitted airborne?
common cold (rhinovirus) chicken pox (varicella zoster virus)
what are examples of viruses transmitted through faecal-oral route?
- hepatits A
- norovirus
- polio virus
where do rhinoviruses have their primary replication?
-upper respiratory tract
where do rotaviruses have their primary replication?
intestinal epithelium
where do papillomaviruses have their primary replication?
epidermis
what are mechanisms of spread of viruses in the body?
- blood stream
- nervous system
- lymphatic system
what are factors affecting where the viruses will infect (tropism)?
- cellular receptors
- host cellular proteases
- temperature of replication
what is viraemia?
when virus enters blood stream
