Integumentary system Flashcards
largest organ of the body that forms a physical barrier between the exteral environment and the internal environment that it serves
to protect and maintain.
integumentary system
outermost layer of skin, provides a waterproof barrier and creates our skin tone.
Epidermis
beneath the epidermis, contains tough connective tissue, hair follicles, and sweat glands.
Dermis
the deeper subcutaneous tissue made of fat (adipose tissue) and connective tissue; is NOT considered part of the skin
Hypodermis
(no blood supply of its own)
avascular
The epidermis is composed of four or five layers or (strata)
stratum basale, spinosum, granulosum, lucidum, and corneum.
Most cells of the epidermis are keratinocytes (keratin cells). which produce keratin, tne fibrous protein that makes the epidermis a tough protective layer.
Keratinocytes
deepest (basal) layer of the epidermis,
Stratum basale
this basal layer contains epidermal cells that receive the most adequate nourishment via _______ of nutrients from the _____
diffusion, dermis
Its cells constantly undergo cell division to produce millions of new cells daily (What layer) (and called)
regeneration, Stratum Basale
Stratum Basale also called
stratum germinativum
About a quarter (1/4) of the cells ni this layer are spidery, brown-to- black pigment-producing cells
melanocytes
As the epidermal layers move away from the dermis and become part of the more superficial layers; cells appear spiky as the skin is prepared for histological examination, but their desmosomes hold tigh
Stratum spinosum (spiny layer)
add color ot the skin and provide protection from UV. Skin tans due to melanin production that increases when exposed to sunlight.
Melanocytes
Upon reaching the stratum granulosum, the layers become
flatter and increasingly full of keratin
Cell division also occur in this layer, but less often than in basal layer.
Stratum spinosum (spiky layer)
Some granules contain _____ that is secreted into the extracellular space; others contains subunits of keratin; at the upper border of this layer, the cells are beginning to die.
waterproofing glycolipid
are specialized adhesive protein complexes that localize to Intercellular junctions and are responsible for maintaining the mechanical Integrity of tissues.
Desmosomes
abundant granules in its cells
Stratum granulosum (granular layer)
Finally, they die, forming a thin translucent band of flattened dead keratinocytes; this latter epidermal layer is not present in al skin regions, it occurs only where the skin is hairless and extra thick, that is, on the palms of the hands and soles of the feet.
Stratum lucidum (clear layer)
the outermost layer, the stratum corneum, is 20 to 30 cells layers thick but it accounts for about three-quarters of epidermal thickness; it rubs and flakes of slowly and steadily as the dandruff familiar to everyone; then, this layer is replaced by cells produced by the division of the deeper stratum basale cells.
Stratum corneum (horny layer)
Cells that are only present in hands and feet
Merkel Cells
The shinglelike dead cell remnants, completely filled with keratin, are referred to as ____ or horny cells.
Cornfied cells
Is an exceptionally tough protein; its abundance in the stratum corneum alows that layer ot provide a durable “overcoat” for the body, which protects deeper cells from the hostile external environment.
Keratin
a pigment that ranges ni color from yelow to brown to black, is produced by special spider-shaped cells called____ found chiefly in the ____
Melanin, Melanocyte, Stratum Basale
As the melanocytes produce melanin, it accumulates within them in membrane-bound granules called_____ these granules then move to the ends of the spidery arms of the melanocytes, where they are taken up by nearby ______
Melanosomes, Keratinocytes
mostly made up of dense connective tissue.
Dermis
The ____ making up the dermis consists of two major regions- the papillary and reticular regions.
dense (fibrous) connective tissue