Integumentary System

Question 1

What cells are in the epidermis?

Answer 1

Langerhans, Merkel cells, melanocytes, keratinocytes

Question 2

What is the purpose of Langerhan cells?

Answer 2

Specialized dendritic cells of skin, present antigens to T cells for adaptive immune response

Question 3

What are Merkel cells?

Answer 3

Sensory cells

Question 4

What composes the connective tissue matrix?

Answer 4

Collagen, elastin, reticulin

Question 5

What do fibroblasts do?

Answer 5

Produces connective tissue, secretes collagen proteins

Question 6

What type of hypersensitivity reaction is uticaria?

Answer 6

Type I

Question 7

What type of hypersensitivity reaction is allergic contact dermatitis?

Answer 7

Type IV

Question 8

What type of hypersensitivity reaction is atopic dermatitis?

Answer 8

Type I

Question 9

What characterizes psoriasis?

Answer 9

Increased epithelial turnover, lack of allowing cells to mature and undergo keratinization which results in thickening and plaques

Question 10

What cytokines are produced in excess in psoriasis?

Answer 10

TNF-a, IL-17, IL-23–all result in rapid growth

Question 11

What causes psoriasis?

Answer 11

Unknown antigen

Question 12

What occurs in inflammatory acne vulgaris?

Answer 12

Follicular wall rupture in closed comedone, sebum expelled into dermis and results in inflammation

Question 13

What are comedones?

Answer 13

Clogged hair follicles in the skin (can be open=blackhead or closed=whitehead)

Question 14

Herpes zoster becomes dormant and infects which neurons?

Answer 14

Sensory (trigeminal and dorsal root ganglia)

Question 15

What are the main types of bacterial skin infections?

Answer 15

Impetigo, cellulitis, folliculitis

Question 16

What is the cause of non-bullous impetigo?

Answer 16

Either S. Aureus or Streptococcus pyogenes

Question 17

What is the cause of bullous impetigo?

Answer 17

S. Aureus

Question 18

What are the two types of nonmelanoma skin cancers?

Answer 18

Squamous cell carcinoma and basal cell carcinoma

Question 19

Which nonmelanoma skin cancer is more likely to metastasize?

Answer 19

Squamous cell carcinoma

Question 20

Which nonmelanoma skin cancer is the most common?

Answer 20

Basal cell carcinoma

Question 21

What is a decubitus ulcer/injury?

Answer 21

Pressure injury

Question 22

Where do keratinocytes divide?

Answer 22

Stratum basale of the epidermis

Question 23

What are the five layers of the epidermis?

Answer 23

Stratus corneum, stratus lucidum, stratus granulosum, stratus spinosum, stratum basale