Integumentary system Flashcards
What is the bodies largest organ?
The skin, which has many layers.
What are the 3 main layers of the skin?
• Epidermis
• Dermis
• Subcutaneous layer
How is the skin a physical barrier?
The stratum corneum is made from layers of tightly bound, heavily keratinised and nucleated cells.
This provides a physical layer against pathogens.
Mildly acidic secretion from the skin also contributes to this.
How is the skin a chemical barrier?
Lipids are secreted by the skin, providing a chemical barrier against water loss.
Antimicrobial peptides are produced by the skin cells and exocrine glands to protect against infection by bacteria and fungi.
What is excretion?
Sweat and sebum have an excretory role.
They remove excess salts and vitamins.
What is the epidermis?
The top layer of the skin.
Explain the structure of the epidermis.
It is made up of stratified squamous epithelium.
It has 5 layers of strata:
• Stratum basale
• Stratum spinosum
• Stratum granulosum
• Stratum lucidum
• Stratum corneum
There is an outer most epithelial tissue and a lower epidermis.
What is the function of the outermost epithelial tissue of the epidermis?
It protects the body from the external environment and has a semi permeable membrane to maintain moisture.
What is the function of the lower epidermis?
Melanin is produced here to protect from UV radiation, preventing sun damage. Which can lead to burns and cancer.
The cells do the lower dermis make vitamin D or cholecalciferol. The production of this is dependant on sunlight. So in the absence of sunlight, this needs to be consumed in food.
Vitamin D is used by the kidneys to help digest calcium in foods.
Explain the structure of the dermis.
This is a layer of connective tissue which helps support the epidermis, as well as making the skin elastic.
It has many blood vessels, nerve endings, hair follicles and exocrine glands (sweat and sebaceous glands).
What is the role of the dermis?
• Supports the dermis.
• Assists in thermoregulation.
• Cutaneous sensation.
What is cutaneous sensation and how does the dermis facilitate this?
There’s 4 types of mechanoreceptors in the dermis, which respond to pressure and vibrations.
These produce the sense of touch.
How does the dermis facilitate excretion?
It contains sweat glands.
These secrete their products onto a surface rather than into the blood.
The main function of sweat is to reduce body temperature, but sweat contains inorganic ions and urea and therefore plays a part in excretion.
It also contains sebaceous glands which excrete sebum, an oily substance.
Sebum keeps the skin slightly acidic, to protect against microbes.
Explain the structure of the subcutaneous layer?
This is made up of adipose tissue or fat cells and connective tissue.
What is the function of the subcutaneous layer?
This allows the skin to move smoothly over the tissues and muscle underneath.
It also shock absorbs to protect organs, muscles and bones from harm.