Integumentary System Flashcards
In latin, Integumentum means…
Covering
Is Epidermis Vascular or Avascular?
Avascular
On the Epidermis, there are keratinocytes undergoing..
kertinisation
There are 5 layers of in the epidermis
BGSLC
1. Stratum Basale (Deep)
2. Stratum Spinosum
3. Stratum Granulosum
4. Stratum Lucidum *
5. Stratum Corneum (Superficial)
*Thick skin only
Journey from stratum basale to stratum corneum is…. days
25 - 45 days
Stratum basale has mitotically (active/inactive) (type) cells.
Active. Cuboidal
Stratum basale cells are attached to the base by …….. and attached to each other by ……
Hemidesmosomes
Desmosomes
stratum spinosum has …… cells that (has/ does not have) central nuclei
polyhedral “pointy”
Has central nuclei
Stratum Granulosum has ……… cell layers thick
3 - 5 cell layers thick
Stratum Lucidum is only present if the skin is…
thick
Does stratum lucidum have nuclei and organelles?
No
Stratum lucidum has translucent layer of flattened ……………
eosinophilic keratinocytes
Stratum corneum is …………layers of ………..cells
15 - 20 layers of squamous keratinised cells
Precentage of Cellls of Epidermis…
Keratinocytes
Epithelial Tactile Cell
Melanocytes
Antigen presenting cell
Keratinocytes (85%)
Epithelial Tactile Cell (7.5%)
Melanocytes (5%)
Antigen presenting cell (2.5%)
Cells of Epidermis: (4)
Keratinocytes
Epithelial Tactile Cell
Melanocytes
Antigen presenting cell
Epithelial Tactile Cell’s Eponym
Merkel cells
Epithelial tactile cells is located in which stratum?
Stratum basale
Tonic receptors are for (light/heavy) touch
light touch
Type I merkel cell slowly adapts to ………..receptor
mechanoreceptor
Melanosomes accumulate as a supra-nuclear cap that
protects the nuclear DNA of keratinocytes from …
UV radiation
Antigen presenting cell’s eponym:
Langerhands cells
melanocytes are derived from ….. (embryonic structure)
Neural crest
Langerhans cells (antigen presenting cells) is derived from
monocytes
melanocytes produce ….. (brown/black pigments)
eumalins
Langerhan cells is located in which stratum?
Stratum Spinosum
Langerhan cells is located in which stratum?
Stratum Spinosum
Dermis has 2 layers:
Papillary and Reticular Layer
Reticular Vs papillary layer
Papillary: Thin. Superficial
Reticular: Thick. Deep
Collagen types in Dermis layers
Papillary: Type I and II collagen
Reticular: Type I irregular Collagen
Tactile Corpuscle Eponym:
Meissner Corpuscle
Lamellar courpuscles eponym:
Pacinian corpuscle
Lamellar corpuscle located in:
Reticular dermis
Hypodermis has a layer of ……… and …tissue
a layer of adipose tissue and loose connective tissue
Nails is plates of … forming hard keratin
Corneocytes
Skin glands: (3)
Sebaceous Glands
Apocrine sweat glands
Eccrine sweat glands
Apocrine vs eccrine sweat glands secretion:
Apocrine: Secrete protein rich sweat. (related to hair follicle)
Eccrine: Secrete salty urea sweat (not related to hair follicle)