Integumentary System Flashcards
Integumentary system is comprised of:
Skin and accessory organs
Characteristics of integumentary system
Largest organ
10-15% of BW
large surface area
Functions of Integumentary system (6)
- Protection/physical barrier
- Sensory/communication
- Excretory
- Homeostasis
- Secretory
- Cutaneous absorption
Thick skin measurements
6.0mm
Thin skin measurements
0.5 mm
Does thickness/texture vary with location?
Yes
Layers of skin
Epidermis
Dermis
Hypodermis (but not technically part of skin)
Epidermis layer #
4-5 layers
Dermis layer #
2 layers
Hypodermis is _____________ tissue
subcutaneous tissue
Outermost/thinnest layer of skin
Epidermis
What cell type is the epidermis made of?
Keratinized stratified squamous epithelium
Epidermis: avascular/vascular?
avascular - nutrients diffuse from dermis
Where is the epidermis derived from?
Ecoderm (germ layer)
Layers of epidermis
5 layers present on thick skin (palms/soles)
4 layers present on thin skin (rest of body)
Layers of epidermis (Deep to superficial)
Stratum basale
Stratum spinosum
Stratum granulosum
Stratum lucidum
Stratum corneum
Stratum Basale cell types
One layer of cuboidal cells - rests on basal lamina
Stratum germinativum made of:
Stratum basale + stratum spinosum
In stratum basale, stem cells CONSTANTLY ______________________
undergo mitosis to renew epidermis
When cells move up and away from vascular supply, what happens?
Cells die
Stratum spinosum cell type
Stratified polygonal-shaped cells
Stratum spinosum layer characteristics
cells interconnected by spine-like projections
cells increase in size and flatten as move upward
Limited mitosis
Stratum granulosum cell type
flattened cells containing dark granules
Stratum granulosum layer characteristics
keratinization begins here (starting to die)
No mitosis (cells die off)
3-5 cell layers thick
Stratum lucidum layer characteristics
ONLY present in palms/soles
no visible nuclei, organelles, or membranes
appears as clear layer filled with keratin
Stratum corneum layer characteristics
25-30 layers of dead, scale like cells, constantly shed
Stratum corneum cell types
Anucleate squamous filled with keratin (part of water barrier)
Hardening and flattening of cells as move to surface
5 cell types of epidermis
Living keratinocytes
Dendritic cells
Tactile cells
Melanocyte
Stem cell
Epidermis Layers Top to Bottom
Stratum corneum
Stratum lucidum
Stratum granulosum
Stratum spinosum
Stratum basale
Keratinocytes synthesize:
keratin
Melanocytes synthesize:
melanin
Where are keratinocytes found?
Most abundant cell type in epidermis
Where are melanocytes found?
scattered in Stratum basale
Where are Dendritic cells found?
Stratum spinosum and stratum granulosum
Where are tactile cells found?
Stratum basale
Function of Dendritic cells
macrophages (clean up guys)
Use of tactile cells
Mechanoreceptors for touch
Areas of acute sensory perceptions
Types of surface patterns
Congenital
Acquired
Congenital surface patterns
Friction of dermal ridges you’re born with
Acquired surface patterns
Friction creases and friction lines acquired with repetitive motion and age
Deep creases in palms
Shallow creases in knuckles and forehead
What gives individuals different tones of skin?
Amount of melanin produced - number of melanocytes are the same between races
Carotene location
Found in epidermal cells - especially stratum corneum
Carotene - is what?
Yellowish pigment
Hemoglobin most prominent where?
Where blood vessels are close to the surface (lips)
O2 rich blood in surface capillaries gives skin pinkish color
Dermis is derived from?
Mesoderm
Layers of dermis
Papillary and reticular
Dermis vascular?
Supplies nutrients to stratum germinativum to undergo mitosis
Thermoregulation (ANS)
Dermis characteristics
Provides support via collagen and elastic fibers
Contains many hair follicles, glands, and nerve endings
Papillary layer (stratum papillarosum) characteristics
Thin (20% of dermis)
Areolar tissue - loose CT allows passage of vessels, WBCs
Dermal papillae and Epidermal ridges fit together to attach dermis to epidermis to prevent slippage
Dermal papillae and epidermal ridges produce?
Fingertips
Reticular layer (stratum reticularosum) characteristics
Thick and tough (80%)
Dense irregular CT
Fibers form lines of tension
Very distensible (stretch)
Sweat glands, lymph vessels, smooth m. (piloerector), hair follicles, nerve endings