Integumentary Flashcards
Dermis develops from the underlying __________.
A) Ectoderm
B) Mesenchyme
C) Endoderm
B) Mesenchyme
Initially, it originated from ectodermal cells.
A) epidermis
B) dermis
C) hypodermis
A) epidermis
Epidermis develops from surface ________.
A) mesoderm
B) ectoderm
C) endoderm
B) ectoderm
Constant supply of new keratinocytes
A) Stratum Basale
B) Stratum spinosum
C) Stratum Granulosum
D) Stratum Lucidum
A) Stratum Basale
Cells are cuboidal or low columnar in a single layer.
A) Stratum Basale
B) Stratum spinosum
C) Stratum Granulosum
D) Stratum Lucidum
A) Stratum Basale
Large, cuboidal to polygonal, some flattened cells
A) Stratum Basale
B) Stratum spinosum
C) Stratum Granulosum
D) Stratum Lucidum
B) Stratum spinosum
2-3 rows of flattened cells.
A) S. Basale
B) S. Granulosum
C) S. Spinosum
D) S. lucidum
B) S. Granulosum
Cytoplasm filled with numerous “keratohyalin”, coarse basophilic granules.
A) S. Basale
B) S. Granulosum
C) S. Spinosum
D) S. lucidum
B) S. Granulosum
Numerous cytoplasmic prickles bound by desmosomes to adjacent cells
A) S. Basale
B) S. Granulosum
C) S. Spinosum
D) S. lucidum
C) S. Spinosum
Cytokeratin (synthetic fibrillar protein) aggregates to form tonofibrils (intracellular fibrils)
A) S. Basale
B) S. Granulosum
C) S. Spinosum
D) S. lucidum
C) S. Spinosum
Germinal layer and mitotic figures
A) S. Basale
B) S. Granulosum
C) S. Spinosum
D) S. lucidum
A) S. Basale
The cells in the stratum basale is bounded by
A) fascia adherens
B) desmosomes
C) hemidesmosomes
D) nexus
C) hemidesmosomes
The tonofibrils in the stratum spinosum converge to _________
Desmosomes
The cytoplasm of stratum granulosum is filled with numerous coarse basophilic granules called ________
Keratohyaline
Few layers of compacted highly refractile eosinophilic cells.
A) S. Basale
B) S. Lucidum
C) S. Granulosum
D) S. Corneum
B) S. Lucidum
It consists of dead and dying cells as well as flat and cornified cells
A) S. Basale
B) S. Lucidum
C) S. Granulosum
D) S. Corneum
D) S. Corneum
Desmosomes are still seen.
A) S. Basale
B) S. Lucidum
C) S. Granulosum
D) S. Corneum
B) S. Lucidum
Deeper layers contain cornified cells with desmosomal junctions, orderly pattern of intracellular keratin
A) S. Basale
B) S. Lucidum
C) S. Granulosum
D) S. Corneum
C) S. Granulosum
This layer of epidermis has wavy clear strip. It also have non-evident organelles & nuclei.
Stratum Lucidum
The cytoplasm of stratum lucidum consist of dense packed filaments in a matrix called _________.
Eleidin
Most superficial layer slough off or “desquamates”
Stratum Corneum
preceded by disruption of desmososmes and internal structure of cells.
Desquamation
Structural changes in keratinization involve the following EXCEPT:
A) Aggregation and arrangement of filaments.
B) Formation of keratocytes
C) Loss of organelles as a result of accumulation of granules
B) Formation of keratocytes.
Correct:
Formation of keratohyaline granules
Can be found in palms and soles only.
A) thick skin
B) thin skin
A) thick skin
It has sebaceous glands
A) thick skin
B) thin skin
C) both A&B
D) NOTA
B) Thin skin
It has sweat gland
A) thick skin
B) thin skin
C) both A&B
D) NOTA
C) both A&B
The following are characteristics of Thin Skin EXCEPT:
A) (+) Sweat glands
B) (+) sebaceous gland
C) (+) stratum Lucidum
D) (+) stratum granulosum
C) (+) stratum Lucidum
Number of layers of epidermis in THICK skin
A) 3
B) 4
C) 7
D) 5
D) 5
Number of layers of epidermis in THIN skin
A) 3
B) 4
C) 5
D) 6
B) 4
The following are cells that can be found in epidermis except
A) keratinocytes
B) melanocytes
C) macrophage
D) merkels
C) macrophage
Correct:
Langerhan cells
Located scattered infrequently in the basal layer & junction of dermis.
A) keratinocytes
B) melanocytes
C) langerhan cells
D) merkel cells
B) melanocytes
Dendritic cells
A) keratinocytes
B) melanocytes
C) langerhan cells
D) merkel cells
C) langerhan cells
Principal cells/ parenchyma
A) keratinocytes
B) melanocytes
C) langerhan cells
D) merkel cells
A) keratinocytes
Antigen-presenting cells, for contact allergic and other cell -mediated response
A) keratinocytes
B) melanocytes
C) langerhan cells
D) merkel cells
C) langerhan cells
Scattered sparsely among basal cell layer and Difficult to distinguish from melanocytes
A) keratinocytes
B) melanocytes
C) langerhan cells
D) merkel cells
D) merkel cells