Integument Flashcards
From what layer of the epidermis are these cells?
Stratum spinosum; this image shows tonofibrils anchored to desmosomes between cells of this epidermal layer
Name the layers of epidermis shown in this image
from superficial to deep: stratum corneum, stratum granulosum, stratum spinosum, stratum basale
How long does it take to replace epidermis?
About 1 month
What are azurophilic granules?
Lysosomes; found in all granulocytes, can be found in monocytes
What is the major difference between thick and thin skin?
The thickness of the stratum corneum
What are some “other” cells found in the epidermis?
Melanocytes, langerhans, merkel’s
Fun facts about melanocytes
Melanocytes are derives from neural crest cells; they reisde in the stratum basale of the epidermis; melanocytes produces melanin in melanosomes; which are phagocytosed by keratinocytes
What are differences in skin tone due to?
The number of melanosomes (NOT the number of melanocytes)
Fun facts about langerhans cells
Langerhans cells are found in all but the most superficial layer of the epidermis (all “living” layers); part of immune response (present antigens to T-lymphocytes); initiate cutaneous hypersensitivity reactions; pale-staining with lots of dendritic processes
Fun facts about Merkel’s cells
These cells are modified keratinocytes that reside in the stratum basale; they form part of “Merkel’s disc”, which senses touch and pressure – do this via granules that modulate the nerve terminal
What kind of glands are sebacious glands?
Holocrine
What is the structure of eccrine glands and where are they found?
Coiled tubular; dermis and hypodermis
What is the structure of appocrine sweat glands and where are they found?
Simple coild tubular; found in axilla and anogenital region; use merocrine secretion
What type of cell (found in epidermis) is this? What is its function?
Langerhan cell - hypersensitivity rxns
What type of cell (found in epidermis) is this? What is its function?
Melanocyte, secrete melanosomes full of melanin
How would you characterize this bone marrow?
Normal (adult) marrow
How would you characterize this bone marrow?
Hypercellular (adult)
How would you characterize this bone marrow?
Hypocellular (adult)
Identify the key features in this image
Megakaryocyte, erythroblastic island, venous sinuses
Where is this tissue located in the body? What cells are indicated by the arrows?
Lung; macrophages
Where is this tissue located in the body and what are the cells pointed out? What do they produce?
Lung; type II alveolar cells, Surfactant
What structure is indicated by the asterisk?
Terminal bronchiole
What granulocytic cells are picture here?
neutrophilic metamelanocyte (L) and band cell (R)
