integrinas Flashcards

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1
Q

funciones de la mec

A

resistencia de tejidos

permite adhesion

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2
Q

composicion de la mec

A

colageno
elastina
proteoglicanos
glucoproteinas

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3
Q

proteinas de la mec

A

fibronectina
laminina
tenascina

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4
Q

que son las CAMs

A

glicoproteinas ubicadas en la superficies celular

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5
Q

interacciones de las CAMs

A
  • celula con celula
  • celula con matriz extracelular
  • matriz con citoesqueleto
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6
Q

que compuestos tiene el citoesqueleto

A

microtubulos: tubulina
microfilamentos: actina
filamentos intermedios: queratina

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7
Q

las CAMs asisten en la

A

adhesion entre celulas para proveer estructura
transmite señales
migracion celular

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8
Q

moleculas de adhesion

A

integrina dos cadenas alfa (con calcio) y beta
caderina
N-cam sin calcio
selectinas

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9
Q

proteinas de matriz

A

fibronectina
enascina
entactina

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10
Q

parte inicial y final de la integrina

PUENTE EN INTEGRINAS

A

NH2 AMINO
COOH CARBOXILO

DE DISULFURO

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11
Q

QUE SON LAS INTEGRINAS Y SUS TIPOS

A

SON PROTEINAS

SE CONOCEN 20 VARIABLES DE BETA
10 VARIABLES DE ALFA
Y CREAN MAS DE 20 VARIANTES
LA B1 ES LA MAS COMUN

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12
Q

A QUE SE UNE LA INTEGRINA

A

A FIRBONECTINA Y ELLA A COLAGENO O ELASTINA

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13
Q

COMO SE CLASIFICAN LAS INTEGRINAS

A

ABREVIACION VLA

EJEMPLO
B1 ALFA 5
VLA-5

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