Integrated Neurohumoral CV control Flashcards
Arterial bp equation
BP = CO x TPR, cardiac output x total peripheral resistance
CO =
SV x HR
What’s the bainbridge reflex
Where if your HR is too low, increasing SV will increase it not decrease it
Where in the brain do the baroreceptors fire
Nucleus Tractus solitarus of the medulla
What are the steps of RAAS activation
- 1 Renin released by juxtaglomerular cells
- 2 Angiotensinogen is cleaves
- 3 angiotensin 1 travels to lungs
- ACE produces angiotensin II
- Aldosterone released from adrenal cortex
- 3 triggers of RAAS activation
- Low renal artery pressure
- Sympathetic stimulation of juxtaglomerular cells
- Decreased Na+ content in ultra filtrate in kidney
Sympathetic action on heart (NT, receptor, effect)
NE, Beta 1, increased chronotropy, inotropy, and dromotropy
Sympathetic action on vasculature (NT, receptor, effect)
NE, alpha 1, constriction (increased resistance, decreased capacitance)
Parasympathetic action on heart (NT, receptor, effect)
Ach, M2, decreased chronotropy, dromotropy
Parasympathetic action on vasculature
Negligible